Authors : Arit Okechukwu Nwogu; E. O. Anyalebechi; I. Elekima

Volume/Issue : Volume 11 - 2026, Issue 5 - May

Google Scholar : https://tinyurl.com/4mkaaau5

Scribd : https://tinyurl.com/mumnuh87

DOI : https://doi.org/10.38124/ijisrt/26May1392

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Abstract : Herbal supplements are slowly becoming g an important part of primary healthcare worldwide with a lot of persons coming down with hepatotoxic disease of the liver. This study aims to provide a significant correlation between increased concentrations of toxic heavy metals in marketed herbal supplement in Port Harcourt and liver cells and tissues This study evaluated the hepatotoxic activity and heavy metal content of some marketed herbal supplements (Deep Seed, Omega Roots, and Jalin Herbal) in Port Harcourt which were analysed for heavy metals (Cadmium, Lead, Nickel, Arsenic and Mercury). Sixty-six (66) albino rats, weighing 150g were randomly selected and acclimatised, after which they were grouped into different treatment groups. All treatments were administered orally once daily for 28 days. After this administration period, blood and liver tissue samples were obtained and used for the analysis of liver function parameters (AST, ALT, ALP, bilirubin, total protein, and albumin) using spectrophotometric methods.

Keywords : Heavy Metal, Infiltration, Liver, Marketed, Herbal Supplements.

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