Authors : Gayathri Rajaram; Charan Prakash Krishnan; Monika Sekar; Tamil Selvi Sriraman

Volume/Issue : Volume 10 - 2025, Issue 7 - July

Google Scholar : https://tinyurl.com/4xmtv9xt

DOI : https://doi.org/10.38124/ijisrt/25jul137

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Abstract : Transferosomes represent a significant innovation in transdermal drug delivery, providing a highly adaptable and effective system for transporting therapeutic agents across the skin. Compared to traditional delivery methods, transferosomes offer enhanced skin permeability, excellent biocompatibility, improved stability, and fewer systemic side effects. Incorporating transferosomes into gel formulations further improves ease of application, patient adherence, and overall therapeutic efficacy. This review emphasizes the importance of key polymers and solvents in the formulation of transferosomes and examines their use in delivering various therapeutic agents, including antimicrobials, anti-inflammatory drugs, antihypertensives, peptides, antipsychotics, and treatments for hair loss. Ultimately, transferosomal gels present a promising and user-friendly approach for both topical and systemic drug delivery in contemporary pharmaceutical science.

Keywords : Transferosomes, Transdermal Drug Delivery, Phospholipids, Skin Penetration, Controlled Release, Drug-Loaded Gels.

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