Authors :
Gongden, J. J; Meshak, J; Chollom, A.M; and Mashingil, P.M; Nnamani, J; Hudu, M
Volume/Issue :
Volume 8 - 2023, Issue 2 - February
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3YblbA8
DOI :
https://doi.org/10.5281/zenodo.7688645
Abstract :
The aqueous extract of spent chamomile tea
was used to synthesize and characterize Cu2+, and Fe3+
complexes and the antifungal activities of the complexes
determined. The physiochemical parameters such as
melting point, colour, percentage yield and solubility test
were studied. The major Phyto-constituents present
were alkaloids, Flavonoids and Tannins, which may be
responsible for pharmacological activities. The extract
and complexes were scanned in the wavelength ranging
from 200-700nm using a UV-Vis spectrophotometer. The
characteristic peaks showed a bathochromic shift in
Copper (II) chloride salt. The Cu2+ and Fe3+ chamomile
complexes with a Hypochromic shift in iron (iii) chloride
salt. FT-IR of the crude extract and complexes contain
alcohols, phenols, alkanes, amines, aromatic amine,
aliphatic amine and alkyl halide in the extract and
complexes with the only aromatic amine in the extract
and alkyl halide in the Fe3+chamomile complex. XRF
analysis determined the element content and their
percentages, showing a significant change in both extract
and complexes, with the Fe3+chamomile complex having
the highest content of 11.7202%. The result of XRD
showed the crystalline size of the complexes using the
Scherrer formula as D= Kλ/β2θcos θ. The crystalline size
was calculated for Cu2+ and Fe3+ complexes with a value
of 73.1nm and 37.1nm, respectively. This shows that the
copper complex is more crystalline. The antifungal study
of the crude extract and complexes was tested on
Aspergillusflavus, Aspergillusniger, Fusarium sp. and
Penicilliumspp. at different concentration (mm/mg) of
12.5, 25, 50, 100 and 200. The complexes were
biologically active and showed enhanced antifungal
activity compared to the free ligand. The copper
complex showed a better antifungal potency compared
to the Iron complex. Chamomile can potentially be used
as an active ingredient in the production of antifungal
drugs.
Keywords :
Copper complex, zinc complex, Chamomile tea, Characterizations, Anti-fungal.
The aqueous extract of spent chamomile tea
was used to synthesize and characterize Cu2+, and Fe3+
complexes and the antifungal activities of the complexes
determined. The physiochemical parameters such as
melting point, colour, percentage yield and solubility test
were studied. The major Phyto-constituents present
were alkaloids, Flavonoids and Tannins, which may be
responsible for pharmacological activities. The extract
and complexes were scanned in the wavelength ranging
from 200-700nm using a UV-Vis spectrophotometer. The
characteristic peaks showed a bathochromic shift in
Copper (II) chloride salt. The Cu2+ and Fe3+ chamomile
complexes with a Hypochromic shift in iron (iii) chloride
salt. FT-IR of the crude extract and complexes contain
alcohols, phenols, alkanes, amines, aromatic amine,
aliphatic amine and alkyl halide in the extract and
complexes with the only aromatic amine in the extract
and alkyl halide in the Fe3+chamomile complex. XRF
analysis determined the element content and their
percentages, showing a significant change in both extract
and complexes, with the Fe3+chamomile complex having
the highest content of 11.7202%. The result of XRD
showed the crystalline size of the complexes using the
Scherrer formula as D= Kλ/β2θcos θ. The crystalline size
was calculated for Cu2+ and Fe3+ complexes with a value
of 73.1nm and 37.1nm, respectively. This shows that the
copper complex is more crystalline. The antifungal study
of the crude extract and complexes was tested on
Aspergillusflavus, Aspergillusniger, Fusarium sp. and
Penicilliumspp. at different concentration (mm/mg) of
12.5, 25, 50, 100 and 200. The complexes were
biologically active and showed enhanced antifungal
activity compared to the free ligand. The copper
complex showed a better antifungal potency compared
to the Iron complex. Chamomile can potentially be used
as an active ingredient in the production of antifungal
drugs.
Keywords :
Copper complex, zinc complex, Chamomile tea, Characterizations, Anti-fungal.
