Authors : Godwin Silas Macheku; Badria Kombe Mushi; Ashraf Yusuph Mahmoud; Twijise Ambah Mwamfup; Neema Ezekiel Kunyaranyara; Jumanne Japhet Karia

Volume/Issue : Volume 11 - 2026, Issue 8 - August

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Google Scholar : https://tinyurl.com/2x4e5k6d

DOI : https://doi.org/10.38124/ijisrt/26aug966

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

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Abstract : Exploratory laparotomy with controlled drainage, tumor debulking, and marsupialization were performed. Histology confirmed serous cystadenoma. Postoperative management included magnesium sulfate for fetal neuroprotection, antenatal corticosteroids for lung maturity, and nifedipine tocolysis. The pregnancy continued uneventfully, culminating in cesarean delivery at 38 weeks of a healthy male infant (3.24 kg). This case highlights the feasibility of conservative surgical management of giant benign ovarian cysts in the second trimester when laparoscopy is unavailable, with good maternal and fetal outcomes.

Keywords : Ovarian Serous Cystadenoma; Pregnancy; Second Trimester; Laparotomy; Marsupialization; Tocolysis; Magnesium Sulfate; Antenatal Corticosteroids.

References :

1. Cathcart AM, Nezhat FR, Emerson J, Pejovic T, Nezhat CH, Nezhat CR. Adnexal masses during pregnancy: diagnosis, treatment, and prognosis. Am J Obstet Gynecol. 2023;228(6):601-612.
2. American College of Obstetricians and Gynecologists. Practice Bulletin No. 174: Evaluation and Management of Adnexal Masses. Obstet Gynecol. 2016;128:e210-e226.
3. Management of ovarian cysts and cancer in pregnancy. Obstet Gynaecol Reprod Med. 2025.
4. Whitecar P, Turner S, Higby MK. Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol. 1999;181:19-24.
5. Sherard GB 3rd, Hodson CA, Williams HJ, et al. Adnexal masses and pregnancy: a 12-year experience. Am J Obstet Gynecol. 2003;189:358-362.
6. Balci O, Gezginc K, Karatayli R, et al. Management and outcomes of adnexal masses during pregnancy: a 6-year experience. J Obstet Gynaecol Res. 2008;34:524-528.
7. Alalade AO, Maraj BH. Management of adnexal masses in pregnancy. Obstet Gynaecol. 2017;19:317-325.
8. Exxcellence. Management of adnexal masses during pregnancy. Updated 2024.
9. Chen L, Ding J, Hua K. Comparative analysis of laparoscopy versus laparotomy in the management of ovarian cyst during pregnancy. J Obstet Gynaecol Res. 2014;40:147-152.
10. Ultrasound and surgical management of large ovarian cysts during pregnancy. Multiple case series and expert reviews, 2016–2025.
11. Timing of surgery for adnexal masses in pregnancy: second-trimester preference. Consensus from obstetric and gynecologic literature.
12. Huge ovarian mucinous cyst adenoma with pregnancy: conservative surgical management by cystectomy. Indian J Gynecol Oncol. 2016.
13. Successful conservative surgical management of ovarian mucinous cystadenoma with silent torsion in pregnancy. Int J Reprod Contracept Obstet Gynecol. 2020.
14. Laparoscopic management of a 20 cm ovarian serous cystadenoma at 20 weeks of pregnancy: A case report. Cureus. 2025.
15. Al Kindi S, et al. Largest serous cystadenoma in the first trimester treated laparoscopically: a case report. Sultan Qaboos Univ Med J. 2017.
16. Rasmussen AS, Christiansen CF, Ulrichsen SP, Uldbjerg N, Nørgaard M. Non-obstetric abdominal surgery during pregnancy and birth outcomes: a Danish registry-based cohort study. Acta Obstet Gynecol Scand. 2020;99:469-476.
17. Haas DM, et al. Tocolytics for delaying preterm birth: a network meta-analysis. Cochrane Database of Systematic Reviews. 2022.
18. A comprehensive update on the management of preterm labor: a narrative review. Related ACOG/SMFM guidance on tocolysis and neuroprotection.
19. ACOG Committee Opinion No. 455 / SMFM recommendations: Magnesium sulfate before anticipated preterm birth for neuroprotection.
20. Antenatal corticosteroids for fetal lung maturity: ACOG Committee Opinion and WHO recommendations (dexamethasone 6 mg IM every 12 h × four doses).