Aim: Intradiploic epidermoid cysts are rare cranial tumors, with the reports on the giant variety being few to date. We report a case of a giant occipital intradiploic epidermoid and review the literature on modalities of management and outcome of giant intradiploic epidermoids. Method: We report a 68-yearold female presenting with a giant occipital intradiploic epidermoid. We did occipital craniectomy excising the lesion sans the dural adhesion to the torcular region. Postoperatively the patient had abatement of symptoms and had an uneventful follow-up. We also reviewed the pertinent literature on giant intradiploic epidermoids. Results: A total of 47 cases were found, with details of the presentation, management, and outcome available for 37 of them. Male dominance with an average of presentation of 46 years was observed. Headache and swelling both were equally reported as the most common symptom and occipital bone was the most common location of the tumor. All cases underwent craniectomy with tumor excision and no recurrence was seen till the last follow-up available. Conclusion: Giant intradiploic epidermoids are rare tumors. Their clinical presentation and tumor characteristics might be different than smaller intradiploic epidermoids, however, they tend to carry a good prognosis if surgical excision is attempted with respect to the location and its proximity to venous sinuses.

Keywords : Intradiploic Epidermoid, Large Intradiploic Epidermoid, Giant Intradiploic Epidermoid.