Authors :
Zineb Kabala; Mouna Bourhafour; Zineb Bouchbika; Nadia Benchekroun; Hassan Jouhadi; Tawfiq Nezha; Souha Sahraoui
Volume/Issue :
Volume 8 - 2023, Issue 7 - July
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/vxd4bewu
DOI :
https://doi.org/10.5281/zenodo.8254161
Abstract :
Mestatic breast carcinoma to the gallbladder is
uncommon. We report the case of a 50-year-old female
woman whose history of the disease dates back to 2018
with diagnosis of right breast luminal B ductal
carcinoma.The patient underwent a Patey then referred
to the radiation oncology department for further
management.A thoraco-abdominopelvic CT scan
performed prior to adjuvant treatment revealed the
presence of two secondary hepatic nodules.A hepatic MRI
was performed revealing two nodular hepatic lesions in
favor of angiomas. The RCP decision was made to begin
adjuvant treatment with hepatic lesion monitoring. The
patient ends her therapy in 2019, with the hepatic lesions
disappearing on the surveillance CT scan, and was put on
tamoxifen with close hepatic monitoring.An abdominal
ultrasound in February 2020 revealed tiny sections of
segment VI and domes and no worrisome focal lesions; an
abdominal MRI scan was ordered, which revealed a liver
with two nodular forms, segment VII and segment VI, as
well as two millimetric nodules.The liver biopsy (PBF)
demonstrated luminal B ductal carcinoma hepatic
location congruent with mammary origin.A CT scan
revealed a liver filled with lesions, a swollen gall bladder
with two macrolithiasis lesions and osteocondensing
lesions, CA 15.3 at 1132 U/ml, and bone scintigraphy
showing hyperfixation of the base of the skull, vertebral,
iliac, right femoral, and right tibial.The RCP considered
the matter again and agreed to put the patient on first-line
therapy antiCD4/6 with letrozole.Two months after the
patient went to the emergency for acute cholecystit a
laparoscopic cholecystectomy was conducted.
Anathomo pathological examination of the specimen
shows a perivesicular immune histochemical appearance
of a poorly differentiated mammary carcinoma
compatible with the luminal B ductal mammary
carcinoma. In view of the progression, the patient was
transferred to 2nd-line and a new extended work-up were
sought, but she died seven days after the appointment.
Keywords :
Breast cancer, ductal carcinoma, gallbladder, acute cholecystit , laparoscopic cholecystectomy
Mestatic breast carcinoma to the gallbladder is
uncommon. We report the case of a 50-year-old female
woman whose history of the disease dates back to 2018
with diagnosis of right breast luminal B ductal
carcinoma.The patient underwent a Patey then referred
to the radiation oncology department for further
management.A thoraco-abdominopelvic CT scan
performed prior to adjuvant treatment revealed the
presence of two secondary hepatic nodules.A hepatic MRI
was performed revealing two nodular hepatic lesions in
favor of angiomas. The RCP decision was made to begin
adjuvant treatment with hepatic lesion monitoring. The
patient ends her therapy in 2019, with the hepatic lesions
disappearing on the surveillance CT scan, and was put on
tamoxifen with close hepatic monitoring.An abdominal
ultrasound in February 2020 revealed tiny sections of
segment VI and domes and no worrisome focal lesions; an
abdominal MRI scan was ordered, which revealed a liver
with two nodular forms, segment VII and segment VI, as
well as two millimetric nodules.The liver biopsy (PBF)
demonstrated luminal B ductal carcinoma hepatic
location congruent with mammary origin.A CT scan
revealed a liver filled with lesions, a swollen gall bladder
with two macrolithiasis lesions and osteocondensing
lesions, CA 15.3 at 1132 U/ml, and bone scintigraphy
showing hyperfixation of the base of the skull, vertebral,
iliac, right femoral, and right tibial.The RCP considered
the matter again and agreed to put the patient on first-line
therapy antiCD4/6 with letrozole.Two months after the
patient went to the emergency for acute cholecystit a
laparoscopic cholecystectomy was conducted.
Anathomo pathological examination of the specimen
shows a perivesicular immune histochemical appearance
of a poorly differentiated mammary carcinoma
compatible with the luminal B ductal mammary
carcinoma. In view of the progression, the patient was
transferred to 2nd-line and a new extended work-up were
sought, but she died seven days after the appointment.
Keywords :
Breast cancer, ductal carcinoma, gallbladder, acute cholecystit , laparoscopic cholecystectomy
