Formulation Design and Evaluation of Mucoadhesive Buccal Patch of Ketorolac for the Treatment of Periodontitis

Authors : Vaishali Barpete; Kuldeep Vinchurkar; Dinesh Kumar Mishra; Pankaj Dixit

Volume/Issue : Volume 6 - 2021, Issue 5 - May

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In the present work the aim is to successfully develop a formulation in the form of buccal patch which has prolong residence time also for addressing the problem of osteoporosis in infected teeth. Patients can control the period of administration or terminate delivery in case of emergencies. The buccal drug delivery systems easily administered into the buccal cavity. The novel buccal dosage forms Exhibits better patient compliance. The formulation F4 is selected for best formulation because its show the 98.85% drug release at time 6 hr, folding endurance is 189+4 times and weight of prepared film is 95+4 mg and thickness 43+2 mm of these formulations respectively.

Keywords : Ketorolac, Mucoadhesive, Formulation and Evaluation of Buccal Film, Solvent Casting, Buccal Film.


Paper Submission Last Date
31 - May - 2022

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