Authors :
Terli Bhargavi Punyayathi
Volume/Issue :
Volume 7 - 2022, Issue 12 - December
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3jiShj2
DOI :
https://doi.org/10.5281/zenodo.7460468
Abstract :
Topical gels have advantages in the
formulation to circumvent the first pass effect, to improve
its bio availability, to reduce dosing frequency and dose
related side effects. Sodium salicylate and salicylic acid
are formulated as topical gels which is used as the
keratolytic or anti-inflammatory agent. Topical gels of
salicylic acid is a BCS class I drug were prepared by
fusion method and characterized by testing for clarity,
homogenesity, spreadibility, melting point, freezing point,
surface pH, drug content uniformity and in-vitro drug
dissolution studies. Nine formulations of salicylic acid and
sodium salicylate topical gels are formulated at different
ratios of polymers like poly ethylene glycols 400 and 4000
and evaluated.
Keywords :
Salicylic Acid, Sodium Salicylate, Transdermal Gel, In-Vitro Drug Release Kinetic Studies, BCS Class I Drug.
Topical gels have advantages in the
formulation to circumvent the first pass effect, to improve
its bio availability, to reduce dosing frequency and dose
related side effects. Sodium salicylate and salicylic acid
are formulated as topical gels which is used as the
keratolytic or anti-inflammatory agent. Topical gels of
salicylic acid is a BCS class I drug were prepared by
fusion method and characterized by testing for clarity,
homogenesity, spreadibility, melting point, freezing point,
surface pH, drug content uniformity and in-vitro drug
dissolution studies. Nine formulations of salicylic acid and
sodium salicylate topical gels are formulated at different
ratios of polymers like poly ethylene glycols 400 and 4000
and evaluated.
Keywords :
Salicylic Acid, Sodium Salicylate, Transdermal Gel, In-Vitro Drug Release Kinetic Studies, BCS Class I Drug.
