Authors : Shibanjan Paul Roy

Volume/Issue : Volume 8 - 2023, Issue 7 - July

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/53v9h89d

DOI : https://doi.org/10.5281/zenodo.8210601

Abstract : My aim of this research proper study was to formulate with evaluate herbal-base cough syrup using Lepidium sativum seed extract. Cough syrup formulations traditionally contain synthetic ingredients, which can have undesirable side effects. Therefore, the use of natural herbal extracts as an alternative is gaining interest. Lepidium sativum, commonly known as garden cress, is known for its medicinal properties and potential therapeutic effects for respiratory conditions. In this study, a cough syrup was developed using Lepidium sativum seed extract, and its effectiveness and safety were evaluated. The cough syrup formulation was prepared by incorporating Lepidium sativum seed extract with suitable excipients. As I know physical and chemical properties of the cough syrup, such as color, odor, viscosity, and pH, were required. The stability of the cough syrup was evaluated under different storage conditions. Additionally, further research most probably required for the cough syrup to in vivo testto determine its potency and efficacy in relieving cough symptoms. The results demonstrated that the formulated cough syrup using Lepidium sativum seed extract had desirable physical and chemical properties. It exhibited a pleasant color and odor, appropriate viscosity, and pH within the acceptable range. The stability studies showed that the cough syrup remained stable under various storage conditions, indicating its potential for commercialization. Our research study revealed that the cough syrup effectively suppressed cough reflexes induced by various irritants. Furthermore, our experiments demonstrated that the cough syrup significantly reduced the frequency and severity of coughing. These findings suggest that Lepidium sativum seed extract will be possesses antitussive properties and can be successfully formulated into a herbal-based cough syrup.But animal study must be required for further research. In conclusion, the developed cough syrup using Lepidium sativum seed extract exhibited promising properties, stability, and antitussive efficacy. The utilization of natural herbal extracts like Lepidium sativum in cough syrup formulations offers a safer alternative to synthetic ingredients. Further studies, including clinical trials, are required to validate the potency, effectiveness and safety of this herbal based cough syrup in animals and humans.

Keywords : Herbal Cough Syrup, Lepidium sativum, Antitussive, Formulation, Evaluation, Stability.