Authors :
Ekenjoku, Azubuike John; Ekenjoku, Theresa Amara; Ekenjoku, Anthony Emeka
Volume/Issue :
Volume 8 - 2023, Issue 7 - July
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/mrx94vy7
DOI :
https://doi.org/10.5281/zenodo.8233382
Abstract :
The fluoroquinolone ciprofloxacin is a potent
antibiotic with proven efficacy against both gram-positive
and especially gram-negative organisms. Because of its
potent activities and successes, it has found tremendous
clinical use in conditions of upper and lower respiratory
tract infections, urinary tract infections, gastrointestinal
tract infections, and many other soft tissue infections. It is
not recommended for use in patients below 12 years due
to the danger of damage to growing cartilage and
arthropathy. Tendonitis is a recognized side effect of
ciprofloxacin and said to be rare, potentially more serious
in adults where it is reported to lead to tendon rupture in
high-risk patients of advanced age, renal insufficiency
and concurrent steroid use.
The following case reports not only confirm the
gravity of this side effect in the elderly but also the
frequency of occurrence. This necessitates attention and
urgent need for vigilance and reassessment of
ciprofloxacin use in the elderly. If further investigations
and reports support this, then the use of Ciprofloxacin in
the elderly should be avoided.
The fluoroquinolone ciprofloxacin is a potent
antibiotic with proven efficacy against both gram-positive
and especially gram-negative organisms. Because of its
potent activities and successes, it has found tremendous
clinical use in conditions of upper and lower respiratory
tract infections, urinary tract infections, gastrointestinal
tract infections, and many other soft tissue infections. It is
not recommended for use in patients below 12 years due
to the danger of damage to growing cartilage and
arthropathy. Tendonitis is a recognized side effect of
ciprofloxacin and said to be rare, potentially more serious
in adults where it is reported to lead to tendon rupture in
high-risk patients of advanced age, renal insufficiency
and concurrent steroid use.
The following case reports not only confirm the
gravity of this side effect in the elderly but also the
frequency of occurrence. This necessitates attention and
urgent need for vigilance and reassessment of
ciprofloxacin use in the elderly. If further investigations
and reports support this, then the use of Ciprofloxacin in
the elderly should be avoided.
