Evaluation of Male Reproductive Hormones in Reserpine Treated Rabbits


Authors : Yetunde O. Akinlaja; Damilare H. Adeyemi; Oluwatobi J. Oyedele; Rukayat A. Mustaph

Volume/Issue : Volume 5 - 2020, Issue 12 - December

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/2X6Xzj2

Depressive disorders are extremely common mental disorders with a life-time prevalence of about 16%. Estimations have shown that by the year 2020 depressive disorders would be the second most significant contributor to the impairment of health globally. This paper is aimed at evaluating the role of reserpine on male reproductive hormones in rabbits. Ten sexually matured rabbits were used for the study, animals were divided into two groups (n=5). Group A (control) was given distilled water, Group B was given reserpine. Blood was collected for via cardiac puncture of the heart and various organs like epididymis, corpus carvenosa and testes were harvested for histological analysis. Data obtained were analyzed using Student’s T-test and p<0.05 was considered significant. The result obtained showed significant reduction in serum testosterone level, while serum LH and FSH level remained unchanged. Epididymal weight result showed significant decrease while testicular weight and corpus carvenosa remained unchanged. The cytoarchitecture of testicular tissue revealed severe damaged to the leydig cell, while that of penile tissue showed loosened connective tissues in corpus spongiosum. This study therefore confirms that reserpine alters serum testosterone levels in male rabbits but the mechanism still remains unclear.

Keywords : Depression; Erectile Dysfunction; Testosterone; Luteinizing Hormone; Follicle Stimulating Hormone; Epididymis

CALL FOR PAPERS


Paper Submission Last Date
31 - May - 2022

Paper Review Notification
In 1-2 Days

Paper Publishing
In 2-3 Days

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe