Ethnopharmacological Investigation o f Ethanolic Extracts of Dual Herbal Combination of Allium Sativum and Lawsonia Inermis


Authors : Ishtiyak Majeed Kumar; Sahlah; Suhailah; Mr. Rashid K; Dr. Sirajudheen. M K

Volume/Issue : Volume 8 - 2023, Issue 7 - July

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/mvvb3527

DOI : https://doi.org/10.5281/zenodo.8237766

Abstract : The upper section of small intestine and inside lining of stomach both can develop open sores called peptic ulcers. Discomfort of stomach is initial symptom of a peptic ulcer. Peptic ulcers include: Stomach ulcers and Duodenal ulcers. Alzheimer's disease is marked by disturbances in nervous system resulting in protein accumulation. The brain shrinks and weakening cells ends up to cell death. Dementia, which is characterised by a slow loss of memory, reasoning, behaviour, and social skills, is primarily caused by Alzheimer's disease. The study begins by documenting the traditional uses and medicinal properties associated with Lawsonia Inermis and Allium sativum This information serves as a foundation for understanding the historical context and traditional knowledge surrounding the herbs. The ethanol extract of Lawsonia Inermis and Allium sativum is prepared using optimized extraction techniques to ensure the maximum extraction of bioactive compounds. The extract is then examined using phytochemical techniques to see whether different secondary metabolites, including phenolic chemicals, alkaloids, flavonoids, and terpenoids, are present. The results of this study contribute to the field of ethnopharmacology by providing evidence for the traditional use of Lawsonia Inermis and Allium sativum in combination. The findings shed light on their synergistic effects, supporting their potential as a natural therapeutic option for peptic ulcer and alzheimers disease. Further research can build upon these findings to develop novel treatments based on this dual herbs combination.

Keywords : Antiulcer, Cholinergic .Invitro chicken Ileum, Lawsonia and Alium

The upper section of small intestine and inside lining of stomach both can develop open sores called peptic ulcers. Discomfort of stomach is initial symptom of a peptic ulcer. Peptic ulcers include: Stomach ulcers and Duodenal ulcers. Alzheimer's disease is marked by disturbances in nervous system resulting in protein accumulation. The brain shrinks and weakening cells ends up to cell death. Dementia, which is characterised by a slow loss of memory, reasoning, behaviour, and social skills, is primarily caused by Alzheimer's disease. The study begins by documenting the traditional uses and medicinal properties associated with Lawsonia Inermis and Allium sativum This information serves as a foundation for understanding the historical context and traditional knowledge surrounding the herbs. The ethanol extract of Lawsonia Inermis and Allium sativum is prepared using optimized extraction techniques to ensure the maximum extraction of bioactive compounds. The extract is then examined using phytochemical techniques to see whether different secondary metabolites, including phenolic chemicals, alkaloids, flavonoids, and terpenoids, are present. The results of this study contribute to the field of ethnopharmacology by providing evidence for the traditional use of Lawsonia Inermis and Allium sativum in combination. The findings shed light on their synergistic effects, supporting their potential as a natural therapeutic option for peptic ulcer and alzheimers disease. Further research can build upon these findings to develop novel treatments based on this dual herbs combination.

Keywords : Antiulcer, Cholinergic .Invitro chicken Ileum, Lawsonia and Alium

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