Authors : Anjali Ojha; Jaspreet Singh Vij; Akanksha Nagar

Volume/Issue : Volume 8 - 2023, Issue 6 - June

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/fz5e96fd

DOI : https://doi.org/10.5281/zenodo.8162623

Abstract : Objectives: To investigate impact of specific physiotherapeutic program on quality of life, anxiety and depression in patients with glioblastoma multiforme and astrocytoma.  Materials and Methods: 20 post surgical Patients with Glioblastoma Multiforme (GBM) and Astrocytoma, aged 45-60 years mean age (55.30 and 53.80), both males and females were randomly included in the study and divided into two groups, group A and group B comprising 10 patients each. All the Patients were assessed for Quality of life using WHO Quality of Life Scale (WHOQOLs) and Functional Assessment of Cancer Therapy- Brain (FACT-BR), anxiety and depression using Hospital based Anxiety and Depression Scale (HADS). The patients of Group A received Specific Physiotherapeutic program, whereas Group B patients received home based exercise regimen. The Patients received interventions for 6 weeks, with 5 weekly sessions.Results: A statistically significant difference was observed in HADS (anxiety and depression) score in Group A (p=0.034) and Group B (p=0.00) whereas statistically non-significant difference was found in WHOQOL scores in Group A (p=0.74) and in Group B (p=0.035) statistically significant difference was observed. The statistically non-significant difference was also documented in FACT-BR (p=0.168) Scores in Group A, FACT-BR (p=0.633) Scores in Group B.  Conclusion: Home based regimen was effective in improving the QOLs and reducing the effect of anxiety and depression in patients with GBM and astrocytoma whereas specific physiotherapeutic program was effective in improving the anxiety and depression.

Keywords : Glioblastoma Multiforme, Astrocytoma, Cancer, Quality of Life, Anxiety and Depression.