Effect of Smoking Dry Cigarettes, Electronic Cigarettes, and Hookah on Vitamin D3 Levels and Blood Parameter in Samples of Youth from AL-Hawija City, Kirkuk governorate


Authors : Abbas Fadhil Khudhur

Volume/Issue : Volume 9 - 2024, Issue 8 - August

Google Scholar : https://tinyurl.com/2s3ns7at

Scribd : https://tinyurl.com/3vvbkhht

DOI : https://doi.org/10.38124/ijisrt/IJISRT24AUG572

Abstract : The study aimed to demonstrate the role of smoking on vitamin D3 levels and blood parameters represented by a group of young men who smoke cigarettes, electronic cigarettes and hookah in the city of Hawija, Kirkuk Governorate. The experiment was distributed into four groups, aged between 25 and 30 years, with 25 samples for each group. The first group was non-smokers, the second group was cigarette smokers, the third group was electronic cigarette smokers and the fourth group was hookah smokers. Blood samples were taken in the Hawija laboratories, where the results of the study showedThe results of the study showed a significant decrease (P≤0.05) in vitamin D3 levels in the dry cigarettes, electronic cigarettes and hookah groups compared to the control group, while the packed cell volume (PCV), red blood cells (RBC) and hemoglobin (Hb) tests showed a significant increase (P≤0.05) in the dry cigarettes, electronic cigarettes and hookah groups compared to the control group, while the platelets and white blood cells (WBC) tests showed a significant increase (P≤0.05) in the dry cigarettes and electronic cigarettes groups compared to the non- smoking control group, while the values of platelets and white blood cells (WBC) did not show any statistically significant differences in the hookah smokers group.

Keywords : Blood Parameters ,Vitamin D; Smoking, Cigarettes; Hookah ,Electrical Cigarettes.

References :

  1. C. Palacios and L. Gonzalez, ‘Is vitamin D deficiency a major global public health problem?’, J. Steroid Biochem. Mol. Biol., vol. 144, pp. 138–145, 2014.
  2. N. M. Al-Daghri, ‘Vitamin D in Saudi Arabia: prevalence, distribution and disease associations’, J. Steroid Biochem. Mol. Biol., vol. 175, pp. 102–107, 2018.
  3. Food and H. H. S. Drug Administration, ‘Food additives permitted for direct addition to food for human consumption; folic acid. Final rule’, Fed. Regist., vol. 81, no. 73, pp. 22176–22183, 2016.
  4. Y. Zhu et al., ‘Vitamin D status and asthma, lung function, and hospitalization among British adults’, Front. Nutr., vol. 9, p. 954768, 2022.
  5. W. Janssens et al., ‘Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene’, Thorax, vol. 65, no. 3, pp. 215–220, 2010.
  6. A. M. Wood, M. J. Simmonds, S. C. Gough, and R. A. Stockley, ‘Variation in the vitamin D binding protein (gc) gene is associated with the presence of bronchiectasis in alpha-1-antitrypsin deficiency’, Am J Respir Crit Care Med, vol. 178, p. A776, 2008.
  7. I. Ito et al., ‘Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele’, Chest, vol. 125, no. 1, pp. 63–70, 2004.
  8. M. J. Sevenoaks and R. A. Stockley, ‘Chronic Obstructive Pulmonary Disease, inflammation and co-morbidity – a common inflammatory phenotype?’, Respir. Res., vol. 7, no. 1, p. 70, Dec. 2006, doi: 10.1186/1465-9921-7-70.
  9. J. E. Repine, A. Bast, I. Lankhorst, and The Oxidative Stress Study Group, ‘Oxidative Stress in Chronic Obstructive Pulmonary Disease’, Am. J. Respir. Crit. Care Med., vol. 156, no. 2, pp. 341–357, Aug. 1997, doi: 10.1164/ajrccm.156.2.9611013.
  10. S. M. Abdullah, S. J. Abdulrahman, and A. A. Hayder, ‘Assessment of the Effect of Propolis Extract on Enzymatic Antioxidants and Lipidperoxidation’, 2024, Accessed: Apr. 24, 2024. [Online]. Available: https://www.researchgate.net/ profile/Adil-Hassan-5/publication/378976972_ Assessment_of_the_Effect_of_Propolis_Extract_on_Enzymatic_Antioxidants_and_Lipidperoxidation/links/65f49a39c05fd2688015d229/Assessment-of-the-Effect-of-Propolis-Extract-on-Enzymatic-Antioxidants-and-Lipidperoxidation.pdf
  11. Y. Kuo et al., ‘Effects of Vitamin D3 on Expression of Tumor Necrosis Factor‐α and Chemokines by Monocytes’, J. Food Sci., vol. 75, no. 6, Aug. 2010, doi: 10.1111/j.1750-3841.2010.01704.x.
  12. S. Hansdottir, M. M. Monick, N. Lovan, L. S. Powers, and G. W. Hunninghake, ‘Smoking Disrupts Vitamin D Metabolism In The Lungs’, in A36. INFLAMMATION AND THE AIRWAY EPITHELIUM, American Thoracic Society, May 2010, pp. A1425–A1425. doi: 10.1164/ajrccm-conference.2010.181.1_MeetingAbstracts.A1425.
  13. K. M. Kunisaki, D. E. Niewoehner, R. J. Singh, and J. E. Connett, ‘Vitamin D status and longitudinal lung function decline in the Lung Health Study’, Eur. Respir. J., vol. 37, no. 2, pp. 238–243, 2011.
  14. L.-P. Boulet, L. Catherine, A. Francine, C. Guy, M. C. Descary, and D. Francine, ‘Smoking and asthma: clinical and radiologic features, lung function, and airway inflammation’, Chest, vol. 129, no. 3, pp. 661–668, 2006.
  15. G. S. Shen et al., ‘Cigarette smoking and risk of hip fracture in women: a meta-analysis of prospective cohort studies’, Injury, vol. 46, no. 7, pp. 1333–1340, 2015.
  16. M. Stürmer, K. Šebeková, G. Fazeli, U. Bahner, F. Stäb, and A. Heidland, ‘25-hydroxyvitamin d and advanced glycation endproducts in healthy and hypertensive subjects: are there interactions?’, J. Ren. Nutr., vol. 25, no. 2, pp. 209–216, 2015.
  17. J. Duncan, ‘Attention, intelligence, and the frontal lobes.’, 1995, Accessed: Aug. 11, 2024. [Online]. Available: https://psycnet.apa.org/record/1994-98810-045
  18. N. Van Der Rijst and J. L. Garfield, ‘Adverse Effects of Tobacco Products (Cigarettes, E-Cigarettes, Hookah, Smokeless Tobacco) Use on Health’, in Tobacco Dependence, M. N. Eakin and H. Kathuria, Eds., in Respiratory Medicine. , Cham: Springer International Publishing, 2023, pp. 23–43. doi: 10.1007/978-3-031-24914-3_2.
  19. H. Jandíková, M. Dušková, and L. Stárka, ‘The influence of smoking and cessation on the human reproductive hormonal balance’, Physiol. Res., vol. 66, pp. S323–S331, 2017.
  20. Y. Fang et al., ‘Ethanol extract of propolis protects endothelial cells from oxidized low density lipoprotein-induced injury by inhibiting lectin-like oxidized low density lipoprotein receptor-1-mediated oxidative stress’, Exp. Biol. Med., vol. 239, no. 12, pp. 1678–1687, Dec. 2014, doi: 10.1177/ 1535370214541911.
  21. S. J. Wimalawansa, ‘Vitamin D deficiency: effects on oxidative stress, epigenetics, gene regulation, and aging. Biology (Basel) 8: 30’. 2019.
  22. L. Barrea et al., ‘Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist’, Rev. Endocr. Metab. Disord., vol. 18, no. 2, pp. 195–205, Jun. 2017, doi: 10.1007/s11154-017-9411-6.
  23. M. Azevedo, L. Bandeira, C. Luza, A. Lemos, and F. Bandeira, ‘Vitamin D deficiency, skin phototype, sun index, and metabolic risk among patients with high rates of sun exposure living in the tropics’, J. Clin. Aesthetic Dermatol., vol. 11, no. 8, p. 15, 2018.
  24. J. Sirola et al., ‘Smoking may impair the bone protective effects of nutritional calcium: a population-based approach’, J. Bone Miner. Res., vol. 18, no. 6, pp. 1036–1042, 2003.
  25. L. E. Crotty Alexander et al., ‘Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice’, Am. J. Physiol.-Regul. Integr. Comp. Physiol., vol. 314, no. 6, pp. R834–R847, Jun. 2018, doi: 10.1152/ajpregu.00270. 2017.
  26. I. Ghinai et al., ‘First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA’, The Lancet, vol. 395, no. 10230, pp. 1137–1144, 2020.
  27. D. Parekh, D. R Thickett, and A. M Turner, ‘Vitamin D deficiency and acute lung injury’, Inflamm. Allergy-Drug Targets Former. Curr. Drug Targets-Inflamm. AllergyDiscontinued, vol. 12, no. 4, pp. 253–261, 2013.
  28. S. M. A. Waseem and A. B. Alvi, ‘Correlation between anemia and smoking: Study of patients visiting different outpatient departments of Integral Institute of Medical Science and Research, Lucknow’, Natl. J. Physiol. Pharm. Pharmacol., vol. 10, no. 2, pp. 149–149, 2020.
  29. A. M. Al Dayyeni, B. T. Al-Gailani, and M. G. Mahdi, ‘The role of erythropoietin levels and other hematological factors in the diagnosis of polycythemia vera in Iraqi patients’, Iraqi J. Hematol., vol. 12, no. 1, pp. 50–56, 2023.
  30. F. Lüdicke, J. Magnette, G. Baker, and R. Weitkunat, ‘A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers’, Biomarkers, vol. 20, no. 6–7, pp. 411–421, Oct. 2015, doi: 10.3109/1354750 X.2015.1096303.
  31. S. Belkin et al., ‘Impact of heated tobacco products, e-cigarettes, and cigarettes on inflammation and endothelial dysfunction’, Int. J. Mol. Sci., vol. 24, no. 11, p. 9432, 2023.
  32. M. K. Al-Hadrawi, Z. S. A. Jabar, A. A. Hasan, and K. A. Hammadi, ‘Study the Effect of Tobacco Smoking (Cigarette and Hookah) on Some Blood Parameters in the Samples of Iraqi People in Al-Najaf Governorate’, Med. J. Babylon, vol. 21, no. Suppl 1, pp. S39–S43, 2024.
  33. F. S. AlQahtany et al., ‘Association between cigarette & shisha smoking and the severity of polycythemia: A cross sectional study’, Saudi J. Biol. Sci., vol. 27, no. 1, pp. 460–464, 2020.
  34. M. M. Nadia, H. A. Shamseldein, and A. S. Sara, ‘Effects of Cigarette and Shisha Smoking on Hematological Parameters: An analytic case-control study’, IMJH, vol. 10, pp. 44–51, 2015.
  35. S. Asgary, G. H. Naderi, and A. Ghannady, ‘Effects of cigarette smoke, nicotine and cotinine on red blood cell hemolysis and their-SH capacity’, Exp. Clin. Cardiol., vol. 10, no. 2, p. 116, 2005.
  36. S. Tamamizu-Kato et al., ‘Modification by Acrolein, a Component of Tobacco Smoke and Age-Related Oxidative Stress, Mediates Functional Impairment of Human Apolipoprotein E’, Biochemistry, vol. 46, no. 28, pp. 8392–8400, Jul. 2007, doi: 10.1021/bi700289k.
  37. K. Kumboyono, K. M. A. Anggara, R. Agustina, M. Lukitasari, and T. A. Wihastuti, ‘Differences in Haemoglobin and Erythrocytes Levels in Smokers and Non-smokers’, in Brawijaya International Conference (BIC 2022), Atlantis Press, 2023, pp. 457–465. Accessed: Aug. 11, 2024. [Online]. Available: https://www.atlantis-press.com/ proceedings/bic-22/125986203
  38. S. Sultana, N. Afsar, M. Jawad, and M. A. H. Hazari, ‘Effects of cigarette smoking on erythrocyte sedimentation rate, platelet count, total and differential leucocyte counts in adult male smokers: Blood parameters effected by cigarette smoking in males’, Ann. Med. Physiol., vol. 3, no. 1, pp. 14–18, 2019.
  39. M. Güden, S. T. Karaman, and O. Basat, ‘Evaluation of the relationship between the level of addiction and exhaled carbon monoxide levels with neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in smokers’, Tob. Induc. Dis., vol. 20, 2022, Accessed: Aug. 11, 2024. [Online]. Available: https://www. ncbi.nlm.nih.gov/pmc/articles/PMC9204713/
  40. K. Kotani, N. Sakane, K. Saiga, H. Mu, and Y. Kurozawa, ‘Clustered components of the metabolic syndrome and platelet counts in Japanese females’, Clin. Chem. Lab. Med., vol. 45, no. 3, Jan. 2007, doi: 10.1515/CCLM.2007.063.

The study aimed to demonstrate the role of smoking on vitamin D3 levels and blood parameters represented by a group of young men who smoke cigarettes, electronic cigarettes and hookah in the city of Hawija, Kirkuk Governorate. The experiment was distributed into four groups, aged between 25 and 30 years, with 25 samples for each group. The first group was non-smokers, the second group was cigarette smokers, the third group was electronic cigarette smokers and the fourth group was hookah smokers. Blood samples were taken in the Hawija laboratories, where the results of the study showedThe results of the study showed a significant decrease (P≤0.05) in vitamin D3 levels in the dry cigarettes, electronic cigarettes and hookah groups compared to the control group, while the packed cell volume (PCV), red blood cells (RBC) and hemoglobin (Hb) tests showed a significant increase (P≤0.05) in the dry cigarettes, electronic cigarettes and hookah groups compared to the control group, while the platelets and white blood cells (WBC) tests showed a significant increase (P≤0.05) in the dry cigarettes and electronic cigarettes groups compared to the non- smoking control group, while the values of platelets and white blood cells (WBC) did not show any statistically significant differences in the hookah smokers group.

Keywords : Blood Parameters ,Vitamin D; Smoking, Cigarettes; Hookah ,Electrical Cigarettes.

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