Cancer, an “umbrella” term for more than 200 types of neoplastic diseases, is characterized by abnormal growth and spread of cells. Health promotion strategies play an important role towards prevention of all kinds of cancer. Aim of the present study is to determine the, “Effectof self-instructed bookleton knowledge about preventive practices of uterine and cervical cancer”. Objectives of the study are; to assess the existing knowledge about preventive practices of uterine and cervical cancer among female patients admitted in medical wards, to assess the effect of selfinstructed bookleton knowledge about preventive practices of uterine and cervical cancer among female patients admitted in medical wards, to associate the pretest knowledge with certain demographic variables such as age, education, domicile, marital status and family history of uterine or cervical cancer.Preexperimental one group pretest and posttest design was used.Data was collected from 50 samples admitted in female medical ward in a selected hospital,Tamilnadu. Structured interview questionnaire used to obtain data before and after intervention. Data was analyzed using descriptive and inferential statistics.It was found that the knowledge level of samples was statistically significant

Keywords : self-instructed booklet, Prevention, uterine and cervical cancer, knowledge, practice.