Authors :
Alen Kinyina; Sarah Chamos; Glorialoveness S Lyimo
Volume/Issue :
Volume 5 - 2020, Issue 8 - August
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/3bqeFyY
DOI :
10.38124/IJISRT20AUG570
Abstract :
Various studies revealed that what matters for
women during labour is short duration painless labour
which results to better birth outcome. Various drugs and
methods used to hasten labour both traditionally and in
modern obstetrics to minimize the risks of prolonged
labour.
To assess the effects of Hyoscine Butylbromide in
shortening active phase of the first stage of labour in term
pregnant women.
This study was designed as a double-blind,
randomized, controlled, clinical trial comparing two
groups of 200 term pregnant women, where by the
intervention group received 20mg of hyoscine
butylbromide intravenously while the control group
received 1ml normal saline via the same route during the
active phase of labour with cervix dilatation confirmed to
be 4-5 centimeters. The progress of labour for both
groups was closely monitored and documented according
to the principles of active management of labour. Both
women and birth attendants were blinded on the contents
of the syringes.
The mean rate of cervical dilatation in cm per hour
in hyoscine group was 2.6±0.9 and in normal saline was
1.8±0.8 the mean difference was statistical significance
(p=<0.05). The duration of the active phase of the first
stage of labour was shorter in hyoscine group
(190.1±128.9) minutes compared to 266.8±123.2 minutes
of normal saline group (P=0.001). The characteristics of
women including mean age, gestational age and parity
were similar in both groups. The Apgar score of hyoscine
group and normal saline group were similar and the
differences were not statistically significant.
Hyoscine butylbromide is effective drug in
shortening the active stage of the first stage of labour in
term pregnant women. The drug has no effect during the
second and the third stage of labour and no obvious
adverse effect to mothers and newborn.
Keywords :
First stage, Hyoscine butylbromide, Labour,Pregnant.
Various studies revealed that what matters for
women during labour is short duration painless labour
which results to better birth outcome. Various drugs and
methods used to hasten labour both traditionally and in
modern obstetrics to minimize the risks of prolonged
labour.
To assess the effects of Hyoscine Butylbromide in
shortening active phase of the first stage of labour in term
pregnant women.
This study was designed as a double-blind,
randomized, controlled, clinical trial comparing two
groups of 200 term pregnant women, where by the
intervention group received 20mg of hyoscine
butylbromide intravenously while the control group
received 1ml normal saline via the same route during the
active phase of labour with cervix dilatation confirmed to
be 4-5 centimeters. The progress of labour for both
groups was closely monitored and documented according
to the principles of active management of labour. Both
women and birth attendants were blinded on the contents
of the syringes.
The mean rate of cervical dilatation in cm per hour
in hyoscine group was 2.6±0.9 and in normal saline was
1.8±0.8 the mean difference was statistical significance
(p=<0.05). The duration of the active phase of the first
stage of labour was shorter in hyoscine group
(190.1±128.9) minutes compared to 266.8±123.2 minutes
of normal saline group (P=0.001). The characteristics of
women including mean age, gestational age and parity
were similar in both groups. The Apgar score of hyoscine
group and normal saline group were similar and the
differences were not statistically significant.
Hyoscine butylbromide is effective drug in
shortening the active stage of the first stage of labour in
term pregnant women. The drug has no effect during the
second and the third stage of labour and no obvious
adverse effect to mothers and newborn.
Keywords :
First stage, Hyoscine butylbromide, Labour,Pregnant.
