Authors :
Dr. Rohit Sane; Dr. Gurudatta Amin; Dr. Pravin Ghadigaonkar; Dr. Aniket Kamble
Volume/Issue :
Volume 11 - 2026, Issue 5 - May
Google Scholar :
https://tinyurl.com/2x8b4apr
Scribd :
https://tinyurl.com/42ruvpj3
DOI :
https://doi.org/10.38124/ijisrt/26May1961
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Background:
Type 2 diabetes mellitus (T2DM) and hypertension are the most prevalent chronic disease comorbidity in India,
sharing pathophysiological mechanisms and compounding each other's end-organ risks. Comprehensive Diabetes Care
(CDC) is a structured Ayurvedic programme integrating Panchakarma-based procedures with dietary modification. While
prior studies have documented CDC's glycaemic effects in general T2DM populations, its simultaneous impact on blood
pressure control in patients with comorbid hypertension has not been evaluated.
Methods:
A retrospective observational study analysed de-identified records of 79 patients with confirmed T2DM and comorbid
hypertension enrolled in the CDC programme across Madhavbaug clinics in the Kolhapur Regional Integrated Centre,
Maharashtra, India. The primary outcomes were change in HbA1c, systolic blood pressure (SBP), and diastolic blood
pressure (DBP) from baseline to post-treatment. Secondary outcomes included body weight, abdominal girth, BMI, and
heart rate. Paired t-tests were used for within-group comparisons. A sensitivity analysis excluding non-responders was prespecified.
Keywords :
Type 2 Diabetes Mellitus; Hypertension; Comprehensive Diabetes Care; Ayurveda; Panchakarma; Hba1c; Blood Pressure; India; Retrospective Study; Integrative Medicine.
References :
- International Diabetes Federation. IDF Diabetes Atlas, 10th edition. Brussels: IDF; 2021. Available at: https://diabetesatlas.org
- Mills KT, Bundy JD, Kelly TN, et al. Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies from 90 Countries. Circulation. 2016;134(6):441–450.
- Sowers JR. Insulin Resistance and Hypertension. Am J Physiol Heart Circ Physiol. 2004;286(5):H1597–H1602.
- Ferrannini E, Cushman WC. Diabetes and Hypertension: The Bad Companions. Lancet. 2012;380(9841):601–610.
- Papatheodorou K, Banach M, Bekiari E, Rizzo M, Edmonds M. Complications of Diabetes 2017. J Diabetes Res. 2018;2018:3086167.
- UK Prospective Diabetes Study Group. Tight Blood Pressure Control and Risk of Macrovascular and Microvascular Complications in Type 2 Diabetes: UKPDS 38. BMJ. 1998;317(7160):703–713.
- Mandole R, Sane R, Amin GA, et al. Role of Comprehensive Diabetes Care (CDC) in Known Diabetes Patients from Marathwada Region. Eur J Biomed Pharm Sci. 2020;7(8):399–405.
- Sane R, Mandole R, Amin GA, et al. Role of Comprehensive Diabetes Care in Known Diabetes Patients from Western Mumbai Region: An Observational Study. Int J Res Med Sci. 2020;8(8):3013–3018.
- Rathod N, Gond B, Kewat M, Tambe A, Puralkar S. Effect of Ayurveda-Based Comprehensive Diabetic Care Program on Glycaemic Control in Type 2 Diabetic Mellitus Patients: An Observational Study. Asian J Med Health. 2023;21(9):18–24.
- Rastogi S, Chiappelli F. Hemodynamic Effects of Sarvanga Swedana (Ayurvedic Passive Heat Therapy): A Pilot Observational Study. AYU. 2013;34(2):154–159.
- Uebaba K, Xu FH, Ogawa H, et al. Psychoneuroimmunologic Effects of Ayurvedic Oil Dripping Treatment. J Altern Complement Med. 2008;14(10):1189–1198.
- Garber AJ, Abrahamson MJ, Barzilay JI, et al. AACE/ACE Comprehensive Diabetes Management Algorithm. Endocr Pract. 2019;25(1):69–100.
- Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of Intensive Glucose Lowering in Type 2 Diabetes. N Engl J Med. 2008;358(24):2545–2559.
- SPRINT Research Group. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2015;373(22):2103–2116.
- Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of Hyperglycaemia in Type 2 Diabetes: A Patient-Centred Approach. Diabetologia. 2015;58(3):429–442.
- Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of Weight Reduction on Blood Pressure: A Meta-Analysis of Randomized Controlled Trials. Hypertension. 2003;42(5):878–884.
- Lean ME, Leslie WS, Barnes AC, et al. Primary Care-Led Weight Management for Remission of Type 2 Diabetes (DiRECT): An Open-Label, Cluster-Randomised Trial. Lancet. 2018;391(10120):541–551.
Background:
Type 2 diabetes mellitus (T2DM) and hypertension are the most prevalent chronic disease comorbidity in India,
sharing pathophysiological mechanisms and compounding each other's end-organ risks. Comprehensive Diabetes Care
(CDC) is a structured Ayurvedic programme integrating Panchakarma-based procedures with dietary modification. While
prior studies have documented CDC's glycaemic effects in general T2DM populations, its simultaneous impact on blood
pressure control in patients with comorbid hypertension has not been evaluated.
Methods:
A retrospective observational study analysed de-identified records of 79 patients with confirmed T2DM and comorbid
hypertension enrolled in the CDC programme across Madhavbaug clinics in the Kolhapur Regional Integrated Centre,
Maharashtra, India. The primary outcomes were change in HbA1c, systolic blood pressure (SBP), and diastolic blood
pressure (DBP) from baseline to post-treatment. Secondary outcomes included body weight, abdominal girth, BMI, and
heart rate. Paired t-tests were used for within-group comparisons. A sensitivity analysis excluding non-responders was prespecified.
Keywords :
Type 2 Diabetes Mellitus; Hypertension; Comprehensive Diabetes Care; Ayurveda; Panchakarma; Hba1c; Blood Pressure; India; Retrospective Study; Integrative Medicine.