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Effect of Comprehensive Diabetes Care Programme on Glycaemic and Blood Pressure Control in Type 2 Diabetes Mellitus Patients with Comorbid Hypertension: A Retrospective Observational Study


Authors : Dr. Rohit Sane; Dr. Gurudatta Amin; Dr. Pravin Ghadigaonkar; Dr. Aniket Kamble

Volume/Issue : Volume 11 - 2026, Issue 5 - May


Google Scholar : https://tinyurl.com/2x8b4apr

Scribd : https://tinyurl.com/42ruvpj3

DOI : https://doi.org/10.38124/ijisrt/26May1961

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Background: Type 2 diabetes mellitus (T2DM) and hypertension are the most prevalent chronic disease comorbidity in India, sharing pathophysiological mechanisms and compounding each other's end-organ risks. Comprehensive Diabetes Care (CDC) is a structured Ayurvedic programme integrating Panchakarma-based procedures with dietary modification. While prior studies have documented CDC's glycaemic effects in general T2DM populations, its simultaneous impact on blood pressure control in patients with comorbid hypertension has not been evaluated.  Methods: A retrospective observational study analysed de-identified records of 79 patients with confirmed T2DM and comorbid hypertension enrolled in the CDC programme across Madhavbaug clinics in the Kolhapur Regional Integrated Centre, Maharashtra, India. The primary outcomes were change in HbA1c, systolic blood pressure (SBP), and diastolic blood pressure (DBP) from baseline to post-treatment. Secondary outcomes included body weight, abdominal girth, BMI, and heart rate. Paired t-tests were used for within-group comparisons. A sensitivity analysis excluding non-responders was prespecified.

Keywords : Type 2 Diabetes Mellitus; Hypertension; Comprehensive Diabetes Care; Ayurveda; Panchakarma; Hba1c; Blood Pressure; India; Retrospective Study; Integrative Medicine.

References :

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  3. Sowers JR. Insulin Resistance and Hypertension. Am J Physiol Heart Circ Physiol. 2004;286(5):H1597–H1602.
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  15. Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of Hyperglycaemia in Type 2 Diabetes: A Patient-Centred Approach. Diabetologia. 2015;58(3):429–442.
  16. Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of Weight Reduction on Blood Pressure: A Meta-Analysis of Randomized Controlled Trials. Hypertension. 2003;42(5):878–884.
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Background: Type 2 diabetes mellitus (T2DM) and hypertension are the most prevalent chronic disease comorbidity in India, sharing pathophysiological mechanisms and compounding each other's end-organ risks. Comprehensive Diabetes Care (CDC) is a structured Ayurvedic programme integrating Panchakarma-based procedures with dietary modification. While prior studies have documented CDC's glycaemic effects in general T2DM populations, its simultaneous impact on blood pressure control in patients with comorbid hypertension has not been evaluated.  Methods: A retrospective observational study analysed de-identified records of 79 patients with confirmed T2DM and comorbid hypertension enrolled in the CDC programme across Madhavbaug clinics in the Kolhapur Regional Integrated Centre, Maharashtra, India. The primary outcomes were change in HbA1c, systolic blood pressure (SBP), and diastolic blood pressure (DBP) from baseline to post-treatment. Secondary outcomes included body weight, abdominal girth, BMI, and heart rate. Paired t-tests were used for within-group comparisons. A sensitivity analysis excluding non-responders was prespecified.

Keywords : Type 2 Diabetes Mellitus; Hypertension; Comprehensive Diabetes Care; Ayurveda; Panchakarma; Hba1c; Blood Pressure; India; Retrospective Study; Integrative Medicine.

Paper Submission Last Date
30 - June - 2026

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