Eco-Friendly One Pot Synthesis of Coumarin Derivatives by Pechmann Condensation using Tamarind Juice as a Biocatalyst

Authors : Dinesh N. Navale; Prasanna B. Ranade; Santosh W. Zote; Dnyaneshwar K. Kulal; Swapnil J. Wagh

Volume/Issue : Volume 8 - 2023, Issue 2 - February

Scribd :


An efficient and eco-friendly synthetic method has been established for synthesis of 7-hydroxy-4-methyl coumarin and its derivatives using tamarind juice as a biocatalyst. The condensation reaction of Substituted phenol with ethyl acetoacetate (EAA) successfully carried out using tamarind juice as a green and efficient catalyst at 90°C in aqueous condition. This green biocatalyst has been utilised effectively for pechmann reaction with good yield of product, easy workup and eco-friendly reaction conditions.

Keywords : Pechmann Reaction, Tamarind Juice, Resorcinol, Ethyl Acetoacetate, Green Synthesis.


Paper Submission Last Date
29 - February - 2024

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