Authors :
Sakshi P. Muley; Nilesh D. Rathod; Dr. Pramod M. Bhosale; Dr. Vitthal G. Kuchake
Volume/Issue :
Volume 11 - 2026, Issue 5 - May
Google Scholar :
https://tinyurl.com/bdzxaca9
Scribd :
https://tinyurl.com/38xmtv2z
DOI :
https://doi.org/10.38124/ijisrt/26May1473
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Acne vulgaris is one of the most common inflammatory skin disorders affecting mainly adolescents and young
adults. It occurs due to excessive sebum production, blockage of hair follicles, bacterial growth and inflammation. Herbal
formulations are gaining importance because they are considered safer and produce fewer side effects compared to synthetic
preparations. The present study aimed to formulate and evaluate a herbal anti-acne gel using neem extract and Aloe vera
as natural active ingredients. Neem possesses antibacterial, anti-inflammatory and antioxidant properties which help in
reducing acne-causing microorganisms, while Aloe vera provides soothing, moisturizing and healing effects on the skin. The
herbal gel was prepared using Carbopol 940 as a gelling agent along with suitable excipients such as propylene glycol, methyl
paraben and triethanolamine. The prepared formulation was evaluated for various parameters including appearance,
homogeneity, consistency, pH, spreadability, washability and irritation test. The gel showed good consistency, smooth
texture, acceptable pH and satisfactory spreadability without causing irritation to the skin. The study concluded that the
formulated herbal anti-acne gel can be used as a safe, effective and economical topical preparation for the management of
acne.
References :
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- Mhaske SB, Walke PA, Abhang DC, Kasar JS. A review article on formulation and evaluation of gels. International Journal of Advanced Research Science, Communication and Technology. 2025 May; 5(6):656. doi:10.48175/568.
- Suryawanshi PA, Azeem MSA, Ramakant SR, Budge PN, Chakurkar PV. A review on the formulation and evaluation of herbal anti-acne gel. Journal of Emerging Technologies and Innovative Research. 2025 Apr;12(4):e293.
- Gunjal A, Hussain F, Pathan M, Mali V, Jadhav A. Formulation and evaluation of poly-herbal anti-acne facewash. International Journal of Pharmaceutical Sciences and Research. 2024;15(1):246-252. https://doi.org/10.13040/IJPSR.0975-8232.
- Ghodke SK, Bagwan LR, Hingne LD. Research of formulation and evaluation of anti-acne gel. International Journal of Creative Research Thoughts. 2021 Dec;9(12):e649. ISSN: 2320-2882.
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- Borse RR, Premchandani LA, Dhankani AR, Pawar SP. Formulation and evaluation of herbal anti-acne gel containing neem and garlic extract. International Journal of Pharmacy & Pharmaceutical Research. 2020 Jan;17(2).
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- Sonkusare S, Yadav P. Formulation of anti-acne gel from Hibiscus, Aloe vera, Neem, Turmeric, Tea tree oil and Rose water. International Journal of Pharmaceutical Sciences. 2026;4(3):2611-2620.
- Fatima Grace X, Joan Vijetha R, Rahul Raj S, Shanthi S, Latha S, Shanmuganathan S. Formulation and evaluation of polyherbal anti-acne gel. Adv J Pharm Life Sci Res. 2015;3(1):5-8.
- Ganjave VP, Nandkumar P, Ghadge RS. Formulation and evaluation of herbal neem face wash. World Journal of Biology Pharmacy and Health Sciences. 2025;24(2):005-010. doi:10.30574/wjbphs.2025.24.2.0956.
- Julia Afrakoma Ansong, Emmanuel Asante, Raphael Johnson, Mariam El Boakye-Gyasi, Noble Kuntworbe, Frederick William Akuffo Owusu, et al. Formulation and evaluation of herbal-based antiacne gel preparations. Scientific World Journal. 2023:1-13. https://doi.org/10.1155/2023/7838299.
- Rowe RC, Sheskey PJ, Quinn ME, editors. Handbook of pharmaceutical excipients. 6th ed. London: Pharmaceutical Press; 2009.
Acne vulgaris is one of the most common inflammatory skin disorders affecting mainly adolescents and young
adults. It occurs due to excessive sebum production, blockage of hair follicles, bacterial growth and inflammation. Herbal
formulations are gaining importance because they are considered safer and produce fewer side effects compared to synthetic
preparations. The present study aimed to formulate and evaluate a herbal anti-acne gel using neem extract and Aloe vera
as natural active ingredients. Neem possesses antibacterial, anti-inflammatory and antioxidant properties which help in
reducing acne-causing microorganisms, while Aloe vera provides soothing, moisturizing and healing effects on the skin. The
herbal gel was prepared using Carbopol 940 as a gelling agent along with suitable excipients such as propylene glycol, methyl
paraben and triethanolamine. The prepared formulation was evaluated for various parameters including appearance,
homogeneity, consistency, pH, spreadability, washability and irritation test. The gel showed good consistency, smooth
texture, acceptable pH and satisfactory spreadability without causing irritation to the skin. The study concluded that the
formulated herbal anti-acne gel can be used as a safe, effective and economical topical preparation for the management of
acne.