Authors :
Dr. Namratha N; Dr. K Kamalaksh Shenoy; Dr. Kavitha; Avin Kumar; Sruthi S
Volume/Issue :
Volume 7 - 2022, Issue 8 - August
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3SiXbZm
DOI :
https://doi.org/10.5281/zenodo.7095238
Abstract :
In the treatment of glial tumors, intensity-modulated
radiation therapy (IMRT) reportedly reduces the highdose irradiation of at-risk organs and decreases the
frequency of adverse events (AEs).The dosimetric
parameter maximum dose (Dmax) received by the optic
structures influence the incidence and severity of
radiation-induced optic neuropathy in patients treated
with radiotherapy to brain. In this study we evaluate the
Dmax and adjust measures in treatment planning in such
a way as to reduce the dose received by the optical
structures.
Thirty patients aged between 21-68 diagnosed with
primary intracranial gliomas were included in this study.
It was a hospital based retrospective, dosimetric,
observational study. Purposive sampling method was
used for all the cases of Glioma during the study period,
who meet the inclusion criteria and the mean of Dmax was
calculated.
Mean of Dmax of all patients were found to be within the
normal limit according to RTOG Dose constraints
In this observational study, the maximum dose delivered
to optic structures such as the optic nerve and chiasma
were within tolerable limits. The occurrence of radiationinduced optic neuropathy in such patients will be highly
unlikely. Therefore, intensity modulated radiation
therapy is the best and preferred modality for the
treatment of glial tumors.
In the treatment of glial tumors, intensity-modulated
radiation therapy (IMRT) reportedly reduces the highdose irradiation of at-risk organs and decreases the
frequency of adverse events (AEs).The dosimetric
parameter maximum dose (Dmax) received by the optic
structures influence the incidence and severity of
radiation-induced optic neuropathy in patients treated
with radiotherapy to brain. In this study we evaluate the
Dmax and adjust measures in treatment planning in such
a way as to reduce the dose received by the optical
structures.
Thirty patients aged between 21-68 diagnosed with
primary intracranial gliomas were included in this study.
It was a hospital based retrospective, dosimetric,
observational study. Purposive sampling method was
used for all the cases of Glioma during the study period,
who meet the inclusion criteria and the mean of Dmax was
calculated.
Mean of Dmax of all patients were found to be within the
normal limit according to RTOG Dose constraints
In this observational study, the maximum dose delivered
to optic structures such as the optic nerve and chiasma
were within tolerable limits. The occurrence of radiationinduced optic neuropathy in such patients will be highly
unlikely. Therefore, intensity modulated radiation
therapy is the best and preferred modality for the
treatment of glial tumors.
