Dosimetric Evaluation of Anterior Visual Pathway Structures I.E Optic Nerve and Chiasma in Adjuvant Radiation Therapy of Glial Tumors Treated Using Intensity Modulated Radiation TherapyAn Observational Study

Authors : Dr. Namratha N; Dr. K Kamalaksh Shenoy; Dr. Kavitha; Avin Kumar; Sruthi S

Volume/Issue : Volume 7 - 2022, Issue 8 - August

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In the treatment of glial tumors, intensity-modulated radiation therapy (IMRT) reportedly reduces the highdose irradiation of at-risk organs and decreases the frequency of adverse events (AEs).The dosimetric parameter maximum dose (Dmax) received by the optic structures influence the incidence and severity of radiation-induced optic neuropathy in patients treated with radiotherapy to brain. In this study we evaluate the Dmax and adjust measures in treatment planning in such a way as to reduce the dose received by the optical structures. Thirty patients aged between 21-68 diagnosed with primary intracranial gliomas were included in this study. It was a hospital based retrospective, dosimetric, observational study. Purposive sampling method was used for all the cases of Glioma during the study period, who meet the inclusion criteria and the mean of Dmax was calculated. Mean of Dmax of all patients were found to be within the normal limit according to RTOG Dose constraints In this observational study, the maximum dose delivered to optic structures such as the optic nerve and chiasma were within tolerable limits. The occurrence of radiationinduced optic neuropathy in such patients will be highly unlikely. Therefore, intensity modulated radiation therapy is the best and preferred modality for the treatment of glial tumors.


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29 - February - 2024

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