Authors :
Vetrichelvan T; Murugan S; Boomiga M; Durgadevi K; Gayathri K; Gowshika S; Jansirani P
Volume/Issue :
Volume 8 - 2023, Issue 7 - July
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/3zpd3zzp
DOI :
https://doi.org/10.5281/zenodo.8227756
Abstract :
Vericiguat (VER) determination in bulk and
tablet dosage form has been made possible by the
development of sensitive, quick, economical and accurate
UV spectrophotometric approach. The 258 nm wavelength
was used for quantification. Beer's law was followed at
concentrations between 5 and 25 g/ml. ICH guidelines
were followed in the method's validation. A statistical
analysis demonstrated that the technique was reliable for
the analysis of VER in tablet dose form. The proposed
technique has been shown to be suitable for routine
analysis and quality control assay of tablet due to its wide
linearity range, sensitivity, accuracy, and simple
procedure.
Keywords :
Vericiquat, Raw Material, UV Method and Tablet Dosage Form.
Vericiguat (VER) determination in bulk and
tablet dosage form has been made possible by the
development of sensitive, quick, economical and accurate
UV spectrophotometric approach. The 258 nm wavelength
was used for quantification. Beer's law was followed at
concentrations between 5 and 25 g/ml. ICH guidelines
were followed in the method's validation. A statistical
analysis demonstrated that the technique was reliable for
the analysis of VER in tablet dose form. The proposed
technique has been shown to be suitable for routine
analysis and quality control assay of tablet due to its wide
linearity range, sensitivity, accuracy, and simple
procedure.
Keywords :
Vericiquat, Raw Material, UV Method and Tablet Dosage Form.
