This study comprises the development and evaluation of an in-situ gelling liquid dosage form of an anti-hypertensive drug. The anti-hypertensive drug used is Amlodipine Besylate (ADB) a long acting calcium channel blocker used for the management of angina and hypertension; the life-threatening conditions require immediate relief.

Keywords : Amlodipine Besylate, Gastric Retention, Antihypertensive, Calcium Channel Blocker, Sodium Alginate, Optimization