It is a well-known fact Libya is a desert and semidesert, has no significant perennial watercourses such as revers, or drinkable lucks, where Less than 2 percent of the country receives enough rainfall for settled agriculture. In the coastal lowlands and surrounded (less than ten percent of Libyan area), where 95 percent of the population are living (30), The climate is warm summers. The summer temperature in the northern coast between 26° C - 40° C and in desert interior is characterized by very hot summers between 40° C and 46° C and extreme diurnal temperature ranges. More than 97 % of Libyan population using groundwater for drinking, domestic and agriculture watering by digging wells. Due to increase of population last 50 years, the demand of groundwater is increased. On other side the ground water is suffering of human excessive use where the ground water become very deep ( 60 – 350 meter deep) , where many areas polluted by several minerals ions dissolved from deep rocks.The aim of this study is to evaluate and determine the concentration of fluoride ion in ground water at from 60 to 260 meter water well deep and focus on spatial distribution of fluoride in Aljfarh region and to discuss the geostatistical contamination and its effecting in fluoride generation and the relationship between excess consuming fluoride and the heath risk assessment via oral and dermal route exposure reveals that the consumers in majority of the region are at considerable noncarcinogenic at higher risk on children and adults. Also finding and helpful in identifying the affected areas at this study area and recommend that the safer options of drinking water should be adopted

Keywords : High Fluoride Groundwater, Drinking Water Safety, Mechanism, Hydrogeochemistry, Human Health Risk Assessment.