Authors :
Agu Paul Maduabuchi
Volume/Issue :
Volume 10 - 2025, Issue 5 - May
Google Scholar :
https://tinyurl.com/y3dejf4z
DOI :
https://doi.org/10.38124/ijisrt/25may2112
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
This study deals with the Design and Construction of medical Electrophoresis Power Pack for Genotype Machine. The
study adopted the Research and Development (R and D) Design using the Cyclic Model Approach. The population this study
tends to cover is the entire society including the male and female. The construction was carried out on a
Veroboard/stripboard while the casing of the project was done with 22cm x 15cm x 5.5cm knock-out box and a buffer
solution tank of 15cm x 13.5cm x 3.5cm using soldering iron and soldering lead and the material used in the Design and
Construction of this Electrophoresis Machine include: two resistors (220ohms/5w), capacitor (68uf/400v), input and output
voltmeter, 13A fuse, Diodes (1N4007), switches, green and red LEDs, dotted Veroboard, jumper wire, flexible AV wire, and
a buffer solution tank. The principal findings or results of this Research include that; when it was subjected to an extreme
voltage of 220-240v during testing, it worked perfectly well without breakdown; the cost of building this project was low,
which figuratively was N6,870.00 compared to other imported electrophoresis machine in the market sold at N15,000.00 and
above; the project was simple in term of its design, easy to operate and carry out maintenance work on. Finally, the successful
construction and testing of this project has demonstrated that more of this foreign apparatus can be properly modernized
to reduce size and cost of purchase. Some recommendations were that Hospitals should introduce Electrophoresis Machine
that can be automated, that is, the machine that contains a thermostat for auto-regulation; Hospitals should introduce
Electrophoresis Machine that has an alarm for job completion indication; Government should empower youths in the field
of Electronics for the production of more digital Electrophoresis machine for genotype testing.
References :
- Adefemi, O.T., Akpan, V.A., Ovabor, J.T., Adekoya, O.G. and Mbamalu, B.E. (2018) Design and Construction of a Low-Cost Hemoglobin Electrophoresis (Genotype) Machine for the Diagnosis of Inherited Genotype Disorder. Path of Science, [Online] 10 (8), pp. 6038–6055 Available from: https://pathofscience.org/index.php/ps/article/download/3248/1554. [Accessed 0n 12 August 2018].
- Babskii, V.G., Zhukov, M.Y. and Yudovich, V.I. (2012) Mathematical theory of electrophoresis. [Online] New York: Springer Science & Business Media. Available from: https://books.google.co.uk/url?id=mszcBwAAQBAJ&pg=PA19&q=http://www.springer.com/shop&linkid=1&usg=AOvVaw0pR8wud7ZdJjq0IALxs6Zp&source=gbs_pub_info_r. [Accessed on 12 August 2018].
- Bier, M. (2013) Electrophoresis: theory, methods, and applications. ed. [Online] : Elsevier. Available from: https://shop.elsevier.com/books/electrophoresis/bier/978-1-4832-2945-4. [Accessed on 11 July 2018].
- Dorst, K. (2015) Frame innovation: Create new thinking by design. ed. [Online] Cambridge: MIT press. Available from: https://books.google.co.uk/url?id=E6R7BwAAQBAJ&pg=PR5&q=http://mitpress.mit.edu&linkid=1&usg=AOvVaw1dDamjxq4jekDYjWt9n1Bb&source=gbs_pub_info_r. [Accessed on 11 July 2018].
- Ekuma, I. (2017).” Design and construction of transformer type electrophoresis power machine”. Unpublished Practical Project. Bio-Medical Engineering Department Federal Teaching Hospital (FETHA II), Abakaliki Ebonyi State.
- Görg, A., Weiss, W. and Dunn, M.J. (2004) Current two‐dimensional electrophoresis technology for proteomics. Proteomics, [Online] 4 (12), pp. 3665–3685 Available from: https://www.academia.edu/download/42535626/Gorg_A._Weiss_W.__Dunn_M.J._Current_two-20160210-22814-183258d.pdf. [Accessed 12 August 2018].
- Joel, G. (2010). Troubleshooting Electronic Devices. Canada Delmar, Canada.
- Onele, O. N. (2006). Design, Construction and Performance Evaluation of the modules for teaching superposition, Maxwell’s mesh and Thevenin’s theorems. Unpublished HND thesis. Department of education (technical). Kaduna polytechnic. Kaduna.
- Perry, S. J. (2018) Design of a Low-Cost Capillary Electrophoresis Laser-Induced Fluorescence System: Lessons Learned When Trying to Build the Lowest Possible Cost System. ed. [Online] London: Brigham Young University. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7819&context=etd. [Accessed on 11 August 2018].
- Portin, P. (1993) The concept of the gene: short history and present status. The Quarterly Review of Biology, [Online] 68 (2), pp. 173–223 Available from: https://doi.org/10.1086/418039. [Accessed on 12 July 2018].
- Tan, H.W., Tran, T. and Chua, C.K. (2016) A review of printed passive electronic components through fully additive manufacturing methods. Virtual and Physical Prototyping, [Online] 11 (4), pp. 271–288 Available from: https://doi.org/10.1080/17452759.2016.1217586. [Accessed on 11 July 2018].
- Winders, J. (2002) Power transformers: principles and applications. ed. [Online] Boca Raton: CRC Press. Available from: https://doi.org/10.1201/9780203910474 [Accessed on 12 July 2018].
This study deals with the Design and Construction of medical Electrophoresis Power Pack for Genotype Machine. The
study adopted the Research and Development (R and D) Design using the Cyclic Model Approach. The population this study
tends to cover is the entire society including the male and female. The construction was carried out on a
Veroboard/stripboard while the casing of the project was done with 22cm x 15cm x 5.5cm knock-out box and a buffer
solution tank of 15cm x 13.5cm x 3.5cm using soldering iron and soldering lead and the material used in the Design and
Construction of this Electrophoresis Machine include: two resistors (220ohms/5w), capacitor (68uf/400v), input and output
voltmeter, 13A fuse, Diodes (1N4007), switches, green and red LEDs, dotted Veroboard, jumper wire, flexible AV wire, and
a buffer solution tank. The principal findings or results of this Research include that; when it was subjected to an extreme
voltage of 220-240v during testing, it worked perfectly well without breakdown; the cost of building this project was low,
which figuratively was N6,870.00 compared to other imported electrophoresis machine in the market sold at N15,000.00 and
above; the project was simple in term of its design, easy to operate and carry out maintenance work on. Finally, the successful
construction and testing of this project has demonstrated that more of this foreign apparatus can be properly modernized
to reduce size and cost of purchase. Some recommendations were that Hospitals should introduce Electrophoresis Machine
that can be automated, that is, the machine that contains a thermostat for auto-regulation; Hospitals should introduce
Electrophoresis Machine that has an alarm for job completion indication; Government should empower youths in the field
of Electronics for the production of more digital Electrophoresis machine for genotype testing.