Authors :
Mohammed Mzyiene; Ouima Justin Dieudonné Ziba; dil Mellouki; Mustapha Ahsaini; Jalal Eddine Elammari; Mohammed Fadl Tazi; Mohammed Jamal Elfassi; Mohammed Sekal; Taoufisiq Harmouch; Moulay Hassan Farih
Volume/Issue :
Volume 6 - 2021, Issue 7 - July
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/3wvkdky
Abstract :
The Buschke-Löwenstein tumor is a rare
tumor. It is a tumor linked to a sexually transmitted
viral infection by the human papillomavirus (HPV) that
develops on the external genitalia and the ano-rectal
region.
Objective: To describe the clinical, anatomopathological
and management characteristics through a series of 18
observations in a North African population.
Methods: We have retrospectively analyzed data from 18
patients in our prospective database since 2010. This
work is based on the exploitation of clinical records, the
interpretation of the radiological balance, the analysis of
therapeutic methods, as well as short- and long-term
developments.
Results: This includes 18 men whose average age is 52.4
years, 12 of whom have risky sexual behaviors with two
men who have sex with men (MSM), chronic smoking,
cannabis addiction, and HIV-positive human
immunodeficiency virus (HIV) for eight patients with
Buschke-Lowenstein tumors treated with full surgical
resection, which remains the reference treatment. All
patients were sexually active. In all patients, the tumors
were exophytic, cauliflower-shaped ulcers dotted with
outbreaks of infection. Most of the shapes seen were
bulky with an average size of 11cm. The location on the
genital area was constant within 9 cases of an invasion on
the thighs and the peri-anal region. No surgical
complications were noted, particularly infectious. A
relapse was noted in one patient, and it was treated with
radiotherapy and surgical recovery. Due to its rarity, the
management of this type of tumor remains uncodified
and a multidisciplinary consultation meeting and
network management in an expert center guarantee a
better therapeutic strategy.
Conclusions: There seems to be a consensus that the
surgical option should be as radical as possible with
organ preservation. Prevention of this tumor is based on
the treatment of acuminate condylomas and the fight
against sexually transmitted infections.
Keywords :
Buschke-Lowenstein Tumor, Surgery, Human Papillomavirus, Radiotherapy, Relapse.
The Buschke-Löwenstein tumor is a rare
tumor. It is a tumor linked to a sexually transmitted
viral infection by the human papillomavirus (HPV) that
develops on the external genitalia and the ano-rectal
region.
Objective: To describe the clinical, anatomopathological
and management characteristics through a series of 18
observations in a North African population.
Methods: We have retrospectively analyzed data from 18
patients in our prospective database since 2010. This
work is based on the exploitation of clinical records, the
interpretation of the radiological balance, the analysis of
therapeutic methods, as well as short- and long-term
developments.
Results: This includes 18 men whose average age is 52.4
years, 12 of whom have risky sexual behaviors with two
men who have sex with men (MSM), chronic smoking,
cannabis addiction, and HIV-positive human
immunodeficiency virus (HIV) for eight patients with
Buschke-Lowenstein tumors treated with full surgical
resection, which remains the reference treatment. All
patients were sexually active. In all patients, the tumors
were exophytic, cauliflower-shaped ulcers dotted with
outbreaks of infection. Most of the shapes seen were
bulky with an average size of 11cm. The location on the
genital area was constant within 9 cases of an invasion on
the thighs and the peri-anal region. No surgical
complications were noted, particularly infectious. A
relapse was noted in one patient, and it was treated with
radiotherapy and surgical recovery. Due to its rarity, the
management of this type of tumor remains uncodified
and a multidisciplinary consultation meeting and
network management in an expert center guarantee a
better therapeutic strategy.
Conclusions: There seems to be a consensus that the
surgical option should be as radical as possible with
organ preservation. Prevention of this tumor is based on
the treatment of acuminate condylomas and the fight
against sexually transmitted infections.
Keywords :
Buschke-Lowenstein Tumor, Surgery, Human Papillomavirus, Radiotherapy, Relapse.
