Laparoscopic surgery “key-hole surgery” is a preferable surgical intervention nowadays and this is attributed to the recent advances over the past decades that allows the surgeons to perform complex interventions through this minimally invasive technique. Owing to its benefits when compared to traditional open surgery, laparoscopic colonic resections has become a corner-stone in management of colon cancer. In order to maintain the continuity of GI tract by performing bowel anastomosis and to extract the resected specimen, an incision (mini-laparotomy) is essential to achieve this. Various incisions has been proposed and used in the current practice as periumbilical incision, Pfannenstiel incision, stoma site extractions incision (SSE) and natural orifice specimen extraction (NOSE). These incisions have different incidences of development of incisional hernias and surgical site infections (SSI). In this article review, we included different specimen harvest incisions after laparoscopic colonic resections and we recommend the use of Pfannenstiel incision as the it has showed to have the lowest risk of development of incisional hernia.