World health organization estimates a global infertility prevalent rate of 10-15%. Male factor constitute about 40-50% of infertility cases. Exposure to environmental pollutants such as di-(2-ethylhexyl) phthalate (DEHP) adversely affects reproductive system tissue differentiation and functions, thereby potentiating male infertility. This study was designed to investigate the impact of oxidative stress induced by DEHP on some semen parameters, as well as serum androgen concentration in adult Wistar rats.

Keywords : Infertility, DI-(2-Ethylhexyl) Phthalate, Oxidative Stress, Semen Quality.