Consequences of Hot Air and/or γ - Rays on Hair Hygiene Post the Application of Protein Conditioner in Rats: Urea, Creatinine, Scanning Electron Micro


Authors : Eskander, S.B., Ezz El Arab, A., Abdel-Gawad, E. I.

Volume/Issue : Volume 3 - 2018, Issue 9 - September

Google Scholar : https://goo.gl/DF9R4u

Scribd : https://goo.gl/aafsHs

Thomson Reuters ResearcherID : https://goo.gl/KTXLC3

Due to the vast growth in the usage of hair care products, proper evaluation of hair damage is essential for considering the impact of cosmetics or devices used on human health. The objective of the submitted work was to assess the effect of hot air and/ or gamma irradiation following the application of a protein conditioner on the urea, creatinine and hair health. Forty eight albino rats were employed in this work, half of them were females and the other half was males. The animals were divided into eight groups, each of six, three of them were males. Rats in group I were fed free on normal food and water (control group). Animals in groups II, III &IV were rubbed with protein for once, twice and three times, respectively, every so often was separated by one week duration. Following each treatment, the rubbed area was exposed to hot air from a blow dryer (95οC) for one minute. Rats in groups V, VI &VII were tracked the same previous treatment exactly, and a week later, they exposed to 10Grays (Gy) single dose whole body gamma irradiation. While, for animals in group VIII, after applying the protein conditioner, they were exposed to10 Gy γ-irradiation without hot air. One week post-irradiation, rats in all groups were anesthetized and blood samples were collected and serum was separated for urea and creatinine analyses. Then, the hairs cut from the protein applying area and subjected to Scanning Electron Microscope examination (SEM) in addition to Fourier Transform Infrared spectrometry (FT‐IR). The obtained data illustrated that urea and creatinine concentrations were increased significantly in both female and male treated groups as compared to the controls .On the other hand, hair density decreased, and alopecia was induced specially, the animals received protein conditioner plus heat and irradiation three times. As indicated, for hair damaged by hot air, in most cases, the amino acids of the cuticle are altered. The hair was very susceptible to chemical changes as a result of exposure to hot air and /or γ- radiation. In conclusion, there is no protein -based conditioner hair smoothing product that can be considered completely safe. It is worth to state that, it’s time to give serious considerations for stopping these treatments using the available protein products. Even if there is not noticed any negative effects as yet, it doesn’t mean that human is immune but cumulative exposure can increases the risk.

Keywords : Hair conditioner, hot air, γ- rays, urea, creatinine, FT-IR, SEM.

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