Authors :
Taiwo Folasade; Durotoluwa M; Adedokun T; Ajanya O; Nnamonu A; Oshaju H; Nwankwo A; Abdullahi B; Ojji B; Alfa J; Odili N
Volume/Issue :
Volume 6 - 2021, Issue 4 - April
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/3ep6PaA
Abstract :
Adrenal hyperplasia is a rare cause of
secondary hypertension1
. Our index case Is 54 year old
community health extension worker, known
hypertensive of 20 years who presented on account of
uncontrolled hypertension with background family
history of hypertension in both parents and siblings.
Methods: we retrieved the case file of the patient from
UATH Data and Record unit.
Results: Patient blood pressure during the period of
evaluation was persistently elevated with mean blood
pressure of 185/115 + 10mmHg while on triple
antihypertensive. Biochemistry result showed severe
hypokalaemia of 2.2mmol/l, aldosterone level was
markedly elevated with value of 33.90ng/dl, serum renin
level of 0.68ng/dl and aldosterone renin-ratio is 49.9,
abdominal CT showed features of bulky adrenal gland
worse on the left.
Conclusion: Clinical impression of Conn’s syndrome
was made based on the above findings. Patient was
placed on spironolactone- an aldosterone antagonist with
other antihypertensive. Patient symptoms resolved, his
blood pressure became normal and the electrolyte
abnormalities corrected at the 6-8weeks of treatment
Keywords :
Adrenal Gland, Conn’s Syndrome, Hypertension, Hypokalaemia
Adrenal hyperplasia is a rare cause of
secondary hypertension1
. Our index case Is 54 year old
community health extension worker, known
hypertensive of 20 years who presented on account of
uncontrolled hypertension with background family
history of hypertension in both parents and siblings.
Methods: we retrieved the case file of the patient from
UATH Data and Record unit.
Results: Patient blood pressure during the period of
evaluation was persistently elevated with mean blood
pressure of 185/115 + 10mmHg while on triple
antihypertensive. Biochemistry result showed severe
hypokalaemia of 2.2mmol/l, aldosterone level was
markedly elevated with value of 33.90ng/dl, serum renin
level of 0.68ng/dl and aldosterone renin-ratio is 49.9,
abdominal CT showed features of bulky adrenal gland
worse on the left.
Conclusion: Clinical impression of Conn’s syndrome
was made based on the above findings. Patient was
placed on spironolactone- an aldosterone antagonist with
other antihypertensive. Patient symptoms resolved, his
blood pressure became normal and the electrolyte
abnormalities corrected at the 6-8weeks of treatment
Keywords :
Adrenal Gland, Conn’s Syndrome, Hypertension, Hypokalaemia
