Patients in the ICU experience
hemodynamic disorders, hemodynamics is the flow of
blood in the body's circulatory system, either through
the magna circulation (large circulation) or parva
circulation (circulation in the lungs). Under normal
conditions, hemodynamics will always be maintained in
a physiological condition with neurohormonal control.
The combination of opioids and benzodiazepines is often
used in the induction and maintenance of anesthesia.
Hemodynamic changes after the combination of the two
drugs caused a significant decrease in the function of the
cardiovascular system. Until now, studies assessing the
effect of sedative drugs on cardiac output are still very
Destination: This study aims to determine the
comparison of fentanyl combined with dexmedetomidine
and fentanyl combined with midazolam on cardiac
output using USCOM in ICU patients at RSUP.H.Adam
Keywords : Fentanyl, Dexmedetomidine, Midazolam, Cardiac Output, ICU.