Objective- Inflammation with
neovascularization leads to elevated intraocular
pressure( IOP) which is only modified risk factor for
acute primary angle closure ( APAC) caused by
decreased aqueous humor outflow from the anterior
chamber. The present study has been planned to
compare the levels of MMPs in aqueous humor of
patients with APAC and aimed to analyse the molar
ratio of MMPs with respect to the other MMPs.
Methods- Aqueous humor samples were collected from
46 healthy control persons ( non-glaucomatous) and 52
APAC patients undergoing cataract surgery. Molar
concentrations of all the MMPs were measured using
multiplexed immunoassays Kit Methods. Statistical
significance was assessed with Mann–Whitney U tests,
and Spearman’s method was used to assess correlations
with age and IOP.
MMP2, MMP9 , Acute primary angle closure.