The aim of this study was to assess and compare the anaesthetic efficacy of 2% lignocaine in combination with 0.5% bupivacaine in 1:1 ratio versus 0.5% bupivacaine for inferior alveolar nerve block in surgical removal of bilateral impacted mandibular third molars. Method: 15 patients (18 to 35 years)who meet the inclusive criteria were included in theintergroup comparison study.Based ontheanaesthetic modality used in this study two groups (A and B) were made. The Groups were given classical inferior alveolar nerve block injection for impaction surgery i.e., Group A were injected with a freshly prepared solution of 1 ml of 2% lignocaine hydrochloride (without adrenaline) admixed with 1ml of 0.5% bupivacaine on one side for surgical removal ofimpacted third molar whereas Group B included same 15 patients but this group candidates received 2 ml of 0.5% plain bupivacaine for surgicalremoval of impacted mandibular third molar oncontralateral side. A time interval of 3-4 weeks was given between the two procedures and the following parameters were evaluated the pain on injection, the onset of anaesthesia,the duration of anaesthesia and the hemodynamic parameters were evaluated.

Keywords : Anaesthetics, Bupivacaine, Impaction, Inferior alveolar nerve block, Lignocaine