Periodontal disease is a multifactorial inflammatory disease associated with oral anaerobic species like Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in the subgingival environment. Traditionally elimination of periopathogen containing biofilms was done by scaling and root planing. Subsequently adjunctive antimicrobial agents such as topical antibiotics and antiseptics were used along with scaling and root planing. Chlorhexidine was commonly used as an adjunct in periodontal therapy. But prolonged use of chlorhexidine may cause mucosal desquamation, tooth staining, altered taste sensation, impaired wound healing and reduced attachment of fibroblast. In recent decades, ozone is considered to be an alternative oral antiseptic agent because it is a stronger antimicrobial agent and does not induce microbial resistance.

Keywords : Chronic Periodontitis;Ozonated Water Irrigation; Subgingival Irrigation; Chlorhexidine Irrigation;Porphyromonas Gingivalis; Aggregatibacter Actinomycetemcomitans.