Clinical Profile of Early Child Hood Epilepsy and Developmental Outcome


Authors : Dr. Smruti Dash Mohapatra; Dr. Sasmita Devi Agrawal; Dr. Ipsa Kujur; Dr. Hemant Agrawal

Volume/Issue : Volume 6 - 2021, Issue 12 - December

Google Scholar : http://bitly.ws/gu88

Scribd : https://bit.ly/34hzMUr

Seizure constitutes 70% of all paediatric neurological problems. The incidence rate of seizure is 144 per 100 000 person-years in infancy.Infants from 1 to 24 months are taken in this study as literature supports the differing semiology in this age group compared to older children and also the neonates.  Objective To know the aetiology, clinical profile and developmental outcome of infants aged 1-24 months with seizures.  Method Children aged 1-24 months with seizure attending OPD/ER/ admitted in Paediatrics ward of Hi-Tech MCH, Bhubaneswar from September2019 – October2021 were included. Febrile seizures and neonatal seizures were excluded. Developmental status was assessed at admission using DASII scales and then followed up at 3months and 6months. EEG, CT & MRI were done in selected cases. Data was analyzed by using appropriate statistical techniques in the form of tables, graphs and diagrams.  Result 92 children (56 male,36 female) were included. Mean age at seizure onset was 6.7months. The most common etiology was perinatal as phyxia(57%). Neurological examination was abnormal in 75% and neuro imaging abnormality was in 71.4%. The most common type of seizure was generalised (69.6%). Developmental delay was found in 82.1%.  Conclusion Perinatal asphyxia is the most common cause of seizures in infants aged 1-24 months and developmental delay is found in 82.1% cases. This study helps us to identify the aetiology of seizure in children aged 1month-24months, know the most common clinical profile prevalent in our setup and also guide us to know the developmental outcome of such children which will allow us to identify and treat the disease early and also prevent any developmental delay

Keywords : Infants, DASII, seizure, developmental assessment, MRI

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