Anti-phospholipid antibody syndrome (APAS)
is defined by the association of at least one clinical event
(vascular occlusion, fetal loss) with the presence of
antibodies to phospholipids, and may be isolated or
associated with systemic lupus erythematosus. The
vascular site of the eye has been described in the literature
and may be the main manifestation.
We report the case of a 21-year-old woman admitted
to the emergency department with a rapid unilateral
decrease in visual acuity. Ophthalmological examination
revealed an occlusion of the central retinal vein . The
diagnosis of SAPL was made during the etiological workup with the presence of anti-cardiolipin antibodies, the
patient was put on anti-platelet aggregation treatment.
The evolution was marked by the occurrence of a
miscarriage, after which the patient was put on
When faced with an occlusion of the central retinal
vein or artery in a young subject, in addition to the
recommended cardiovascular check-up, a thrombophilia
and SAPL check-up is essential in order to avoid a
thrombotic recurrence which can be life-threatening if it
is a cerebral location.
Anti Phospholipid Antibody, Thrombosis, Central Retinal Vein