Authors :
Anushka K. Mali; Sakshi M. Shivade; Pranjal S. Vekhande; Tejas T. Pawar; Mansi R. jadhav; Karuna G. Dahale
Volume/Issue :
Volume 10 - 2025, Issue 4 - April
Google Scholar :
https://tinyurl.com/56m89xj9
Scribd :
https://tinyurl.com/5anudsk6
DOI :
https://doi.org/10.38124/ijisrt/25apr1496
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Abstract :
Catharanthus roseus (L.) G. Don, Frequently known as Madagascar periwinkle, is a medicinal plant of significant
therapeutic importance. Belonging to the Apocynaceae family, it is well-known for producing valuable alkaloids such as
vincristine and vinblastine, which are extensively used in cancer chemotherapy. Traditionally, the plant has been used to
treat ailments such as diabetes, hypertension, and microbial infections. Pharmacologically, it exhibits anticancer,
antidiabetic, antimicrobial, and antioxidant activities. The plant is characterized morphologically by its glossy green leaves,
pink or white flowers, and slender stems. Various dosage forms including extracts, tablets, and injectable formulations have
been developed from its active constituents. Despite its medicinal benefits, C. roseus may cause side effects such as nausea,
hair loss, and myelosuppression, especially when used in high doses or for prolonged periods. The diverse chemical
constituents and pharmacological potential of C. roseus make it a critical plant in both traditional and modern medicine.
Keywords :
Medicinal Plant, Plant Extract Process, Pharmacological Effect, Dosage Form , Traditional uses.
References :
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- Ayush Sah, Santoshi Shah, Dr. S.M. Patil, A review on Catharanthus roseus, by IJNRD, Volume 8, 5 May 2023.
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- Raviña, Enrique (2011). "Vinca alkaloids". The evolution of drug discovery: From traditional medicines to modern drugs. John Wiley & Sons. pp. 157–159. ISBN 978-3-527-32669-3.
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Catharanthus roseus (L.) G. Don, Frequently known as Madagascar periwinkle, is a medicinal plant of significant
therapeutic importance. Belonging to the Apocynaceae family, it is well-known for producing valuable alkaloids such as
vincristine and vinblastine, which are extensively used in cancer chemotherapy. Traditionally, the plant has been used to
treat ailments such as diabetes, hypertension, and microbial infections. Pharmacologically, it exhibits anticancer,
antidiabetic, antimicrobial, and antioxidant activities. The plant is characterized morphologically by its glossy green leaves,
pink or white flowers, and slender stems. Various dosage forms including extracts, tablets, and injectable formulations have
been developed from its active constituents. Despite its medicinal benefits, C. roseus may cause side effects such as nausea,
hair loss, and myelosuppression, especially when used in high doses or for prolonged periods. The diverse chemical
constituents and pharmacological potential of C. roseus make it a critical plant in both traditional and modern medicine.
Keywords :
Medicinal Plant, Plant Extract Process, Pharmacological Effect, Dosage Form , Traditional uses.