Case Report: Stiff Person Syndrome (SPS)


Authors : Dr. Tanya Wadhwa

Volume/Issue : Volume 8 - 2023, Issue 6 - June

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/4rec52u5

DOI : https://doi.org/10.5281/zenodo.8082183

Abstract : Stiff Person Syndrome (SPS), a rare autoimmune disorder, which is not widely studied is illustrated in this case report. The patient, a 52-year-old female with Stiff Person Syndrome, presents with spasticity, muscle aches, and weakness. Elevated levels of anti-glutamic acid decarboxylase (GAD) antibodies were detected, confirming the diagnosis of Stiff Person Syndrome. The patient is being treated with Diazepam, Baclofen, IVIG, and Gabapentin. This cocktail of medication has alleviated her pain and stiffness. She is currently responding well to the administered treatment. Early diagnosis and interdisciplinary treatment are necessary for Stiff Person Syndrome to improve patient outcomes and raise quality of life. The relevance of examining SPS as a possible diagnosis in patients who appear with increasing muscle stiffness and spasms is highlighted by this case report, which also underlines the need for more studies to fully comprehend this complicated condition.

Keywords : Stiff Person Syndrome, Autoimmune, Muscular Rigidity, Anti GAD Antibodies, IVIG, Gabapentin.

Stiff Person Syndrome (SPS), a rare autoimmune disorder, which is not widely studied is illustrated in this case report. The patient, a 52-year-old female with Stiff Person Syndrome, presents with spasticity, muscle aches, and weakness. Elevated levels of anti-glutamic acid decarboxylase (GAD) antibodies were detected, confirming the diagnosis of Stiff Person Syndrome. The patient is being treated with Diazepam, Baclofen, IVIG, and Gabapentin. This cocktail of medication has alleviated her pain and stiffness. She is currently responding well to the administered treatment. Early diagnosis and interdisciplinary treatment are necessary for Stiff Person Syndrome to improve patient outcomes and raise quality of life. The relevance of examining SPS as a possible diagnosis in patients who appear with increasing muscle stiffness and spasms is highlighted by this case report, which also underlines the need for more studies to fully comprehend this complicated condition.

Keywords : Stiff Person Syndrome, Autoimmune, Muscular Rigidity, Anti GAD Antibodies, IVIG, Gabapentin.

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