Authors : Dr. Paawan S Chordiya; Dr. Ashwin Patil; Dr. Santosh Patil; Dr. Pradeep Goudar

Volume/Issue : Volume 10 - 2025, Issue 3 - March

Google Scholar : https://tinyurl.com/4mtvj2hh

Scribd : https://tinyurl.com/22hh738c

DOI : https://doi.org/10.38124/ijisrt/25mar1485

Google Scholar

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Note : Google Scholar may take 15 to 20 days to display the article.

Abstract : Background: Central neurocytoma (CN) is a rare, well-differentiated neuroepithelial tumor, classified as WHO Grade 2. It primarily arises within the ventricles, most commonly in the lateral ventricles, and accounts for less than 1% of all intracranial tumors. Due to its location and imaging characteristics, CN poses a diagnostic challenge and may be mistaken for other intraventricular neoplasms.  Case Presentation We present a case of a 28-year-old female who presented with headache, vomiting, and giddiness for two days. MRI brain revealed a heterogeneously enhancing intraventricular mass lesion in the frontal horn and body of the right lateral ventricle, causing obstruction at the foramen of Monro and leading to ventricular dilatation. Imaging features, including T2 hyperintensity, diffusion restriction, and a glycine peak on MR spectroscopy, suggested a neurocytoma. Neurosurgical biopsy confirmed central neurocytoma (CNS WHO Grade 2) based on histopathological and immunohistochemical findings.  Discussion The patient’s symptoms were due to obstructive hydrocephalus, a common presentation of CN. MRI played a crucial role in identifying the lesion, distinguishing it from differential diagnoses such as ependymoma, astrocytoma, and meningioma. Complete surgical resection remains the preferred treatment, with a generally favourable prognosis.  Conclusion Early recognition of CN on MRI is essential for prompt surgical intervention. Given its benign behaviour and low recurrence rate, CN has an excellent prognosis if completely excised. Radiologists must be aware of its imaging characteristics to aid in accurate diagnosis and appropriate surgical planning.

References :

1. Chen CL, Shen CC, Wang J, Lee HT. Central neurocytoma: A clinical, radiological, and pathological study of nine cases. J Clin Neurosci. 2012;19(4):523–8.
2. Hassoun J, Gambarelli D, Grisoli F, Pellet W, Salamon G, Pellissier JF. Central neurocytoma: An electron-microscopic study of two cases. Acta Neuropathol. 1982;56(2):151–6.
3. Koeller KK, Sandberg GD. From the archives of the AFIP: Central neurocytoma—Radiologic-pathologic correlation. Radiographics. 2002;22(6):1257–72.
4. Leenstra JL, Rodriguez FJ, Frechette CM, Giannini C, Stafford SL, Pollock BE. Central neurocytoma: Management recommendations based on a 35-year experience. Int J Radiat Oncol Biol Phys. 2007;67(4):1145–54.
5. Sharma MC, Deb P, Sharma S, Sarkar C, Suri V. Central neurocytoma: A clinicopathological study of seven cases with review of the literature. Neurol India. 2006;54(1):30–6.
6. Rades D, Schild SE, Tatagiba M. Role of postoperative radiotherapy for central neurocytoma: A systematic review. J Neurooncol. 2013;115(3):385–92.
7. Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK. The 2016 World Health Organization classification of tumors of the central nervous system. Acta Neuropathol. 2016;131(6):803–20.
8. Brandes AA, Vastola F, Basso U, Pasetto LM. Central neurocytoma: A study of treatment approaches and clinical outcome in 21 patients. Cancer. 2003;98(1):133–40.
9. Yang I, Wang PI, Tihan T, McDermott MW, Parsa AT. Central neurocytoma: Clinical characteristics, prognostic factors, and review of the literature. Neurosurg Focus. 2005;19(5):E5.