Acute Biliary pancreatitis is a clinical condition that is commonly encountered in surgical emergencies and can have high mortality. It is difficult to identify patients that can have a fulminant course. This study analyses the relationship between CTSI score, morbidity, and mortality. 219 patients admitted to the Department of General Surgery, IGMC, Shimla with acute gallstone-induced pancreatitis were the subjects of our prospective observational study. We tried to establish a relationship between CTSI, morbidity, and mortality.  Results In total, 36 of 219 (13.69%) patients with acute GSP developed severe pancreatitis of whom 11 patients had the edematous type of pancreatitis and 25 had necrotizing pancreatitis. Of these 25 patients, 8 had CTSI of 4-6 and 17 had CTSI of 7-10. CTSI had a direct relation with clinical severity (p =0.044) and morbidity (p=0.031). Mortality was seen in patients who had a CTSI of 7 – 10 (p =0.134). Patients having high CTSI are associated with increased morbidity and clinical severity when compared to patients with low CTSI but a direct correlation with mortality could not be established

Keywords : CTSI, Acute Gall Stone Induced Pancreatitis, Mortality, Morbidity