Authors :
Dr. Sheyon Yohannan; Dr. Dhruv Kumar Sharma
Volume/Issue :
Volume 8 - 2023, Issue 2 - February
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3IUGjq5
DOI :
https://doi.org/10.5281/zenodo.7677954
Abstract :
Early identification of high-risk patientsin a common
emergency like acute gallstone-induced pancreatitis can be
difficult. In patients with acute gallstone-induced
pancreatitis, persistent organ failure is considered to be the
most important cause of mortality. This study strives to
understand the relationship between persistent organ
failure with infected pancreatic necrosis and its
relationship with mortality.
Design
We performed a prospective observational study of
219 patients diagnosed with acute gallstone-induced
pancreatitis who were admitted to the Department of
General Surgery, IGMC, Shimla. We tried to understand
the relationship between the type of organ failure (single
or multiorgan and systemic), infected pancreatic necrosis,
and mortality.
Results
In total, 30 of 219 (13.69%) patients with acute GSP
developed Persistent Organ Failure (of any type or
combination) of whom 15 (6.8%) patients developed an
infection of pancreatic necrosis. Mortality was seen in
patients who had a concomitant infection of pancreatic
necrosis and persistent organ failure (36.36% vs 0%,
p=0.04).
Conclusion
In patients with infection of pancreatic necrosis,
persistent organ failure is associated with increased
mortality when compared to patients with absent
persistent organ failure. As mortality was absent in
patients without infected pancreatic necrosis, the impact
on mortality is debatable.
Keywords :
Infected Pancreatic Necrosis, Persistent Organ Failure, Acute Gall Stone Induced Pancreatitis, Mortality.
Early identification of high-risk patientsin a common
emergency like acute gallstone-induced pancreatitis can be
difficult. In patients with acute gallstone-induced
pancreatitis, persistent organ failure is considered to be the
most important cause of mortality. This study strives to
understand the relationship between persistent organ
failure with infected pancreatic necrosis and its
relationship with mortality.
Design
We performed a prospective observational study of
219 patients diagnosed with acute gallstone-induced
pancreatitis who were admitted to the Department of
General Surgery, IGMC, Shimla. We tried to understand
the relationship between the type of organ failure (single
or multiorgan and systemic), infected pancreatic necrosis,
and mortality.
Results
In total, 30 of 219 (13.69%) patients with acute GSP
developed Persistent Organ Failure (of any type or
combination) of whom 15 (6.8%) patients developed an
infection of pancreatic necrosis. Mortality was seen in
patients who had a concomitant infection of pancreatic
necrosis and persistent organ failure (36.36% vs 0%,
p=0.04).
Conclusion
In patients with infection of pancreatic necrosis,
persistent organ failure is associated with increased
mortality when compared to patients with absent
persistent organ failure. As mortality was absent in
patients without infected pancreatic necrosis, the impact
on mortality is debatable.
Keywords :
Infected Pancreatic Necrosis, Persistent Organ Failure, Acute Gall Stone Induced Pancreatitis, Mortality.