Authors :
Ketan Tamhane; Akanksha Jadhav
Volume/Issue :
Volume 9 - 2024, Issue 3 - March
Google Scholar :
https://tinyurl.com/5eejk3zx
Scribd :
https://tinyurl.com/5p58r4a3
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24MAR416
Abstract :
Breast cancer is marked by uncontrolled cell
growth leading to invasive tumors in the breast ducts
and lobules. Risk factors include modifiable elements
like lifestyle choices and nonmodifiable factors such as
age and genetic mutations. Global epidemiology sheds
light on prevalence and contributing factors, crucial for
prevention and management. Classification involves
histopathological and molecular criteria, encompassing
various subtypes. Diagnosis relies on imaging
techniques like mammography and biopsies, with
minimal radiation exposure. Treatment includes
hormone treatment, targeted therapy, radiation,
chemotherapy, surgery, and immunotherapy, with
immune checkpoint inhibitors such as PD-1 and PDL-1
being used in particular. The intricate tumor
microenvironment involves diverse cell types and
factors like hypoxia and exosomes, presenting
challenges and opportunities for therapeutic
advancements in the breast cancer management.
Keywords :
Breast Cancer; Biopsy; Chemotherapy; Tumor-Resistance; Microenvironment.
Breast cancer is marked by uncontrolled cell
growth leading to invasive tumors in the breast ducts
and lobules. Risk factors include modifiable elements
like lifestyle choices and nonmodifiable factors such as
age and genetic mutations. Global epidemiology sheds
light on prevalence and contributing factors, crucial for
prevention and management. Classification involves
histopathological and molecular criteria, encompassing
various subtypes. Diagnosis relies on imaging
techniques like mammography and biopsies, with
minimal radiation exposure. Treatment includes
hormone treatment, targeted therapy, radiation,
chemotherapy, surgery, and immunotherapy, with
immune checkpoint inhibitors such as PD-1 and PDL-1
being used in particular. The intricate tumor
microenvironment involves diverse cell types and
factors like hypoxia and exosomes, presenting
challenges and opportunities for therapeutic
advancements in the breast cancer management.
Keywords :
Breast Cancer; Biopsy; Chemotherapy; Tumor-Resistance; Microenvironment.
