Authors :
Amrita Mohanty; Gowhar Iqbal; Lukram Sushil Singh; Viral Kumar Ganpatbhai
Volume/Issue :
Volume 8 - 2023, Issue 7 - July
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/4yn5r2uc
DOI :
https://doi.org/10.5281/zenodo.8181065
Abstract :
Naturally, mRNA is a single-stranded
structure consisting of an (m7g) 7-methyl-guanosine
position at 5’end and 3’end consisting of a poly (A) tail.
mRNA has emerged as a novel potential drug candidate
and has wide applications in cancer immunotherapy,
gene therapy, infectious disease vaccines, and cellular
genetic engineering. Extension of the half-life of mRNA
can be achieved by introducing some stabilizing elements
into UTR regions. Employing mRNA for its
therapeutical prospects holds various characteristics
such as simple modifications, faster and transitory
presentation, and compatibility lacking mutagenesis,
which are important for treating various diseases.
mRNA has emerged as a novel potential drug candidate
and has wide applications in cancer immunotherapy,
gene therapy, infectious disease vaccines, and cellular
genetic engineering. In recent years, mRNA has proved
itself a novel therapeutic drug.
Keywords :
mRNA, Therapeutics, Immunotherapy, mRNA Delivery,
Naturally, mRNA is a single-stranded
structure consisting of an (m7g) 7-methyl-guanosine
position at 5’end and 3’end consisting of a poly (A) tail.
mRNA has emerged as a novel potential drug candidate
and has wide applications in cancer immunotherapy,
gene therapy, infectious disease vaccines, and cellular
genetic engineering. Extension of the half-life of mRNA
can be achieved by introducing some stabilizing elements
into UTR regions. Employing mRNA for its
therapeutical prospects holds various characteristics
such as simple modifications, faster and transitory
presentation, and compatibility lacking mutagenesis,
which are important for treating various diseases.
mRNA has emerged as a novel potential drug candidate
and has wide applications in cancer immunotherapy,
gene therapy, infectious disease vaccines, and cellular
genetic engineering. In recent years, mRNA has proved
itself a novel therapeutic drug.
Keywords :
mRNA, Therapeutics, Immunotherapy, mRNA Delivery,
