Authors :
Soujanya Jain Brahmaraj; U. M. Vinay; Tejaswini K. S.; Vinay Kumar B. M.; Pallavi S.
Volume/Issue :
Volume 11 - 2026, Issue 7 - July
Google Scholar :
https://tinyurl.com/2zp8rkvu
Scribd :
https://tinyurl.com/3p42mpzu
DOI :
https://doi.org/10.38124/ijisrt/26jul715
Note : A published paper may take 4-5
working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
Counterfeit medicines have become a major challenge in pharmaceutical supply chains, leading to serious risks
for patient safety and healthcare reliability. Traditional medicine tracking systems mainly rely on centralized databases
and static QR verification methods, which are vulnerable to data manipulation and QR duplication attacks. To address
these issues, this paper proposes a Blockchain-Based Drug Traceability and Intelligent Counterfeit Detection System that
enhances medicine verification using blockchain technology and software-level counterfeit detection mechanisms.
The proposed system integrates blockchain-based medicine registration, QR code verification, ownership transfer
tracking, scan history monitoring, and suspicious activity detection to improve transparency and traceability across the
pharmaceutical supply chain. Medicines are registered and stored securely using smart contracts, while QR codes are
generated for product verification. In addition, the system identifies possible counterfeit activities through duplicate scan
detection, ownership validation, repeated scan monitoring, and already-sold product verification.
The system is implemented using React.js for the frontend, Node.js and Express.js for backend services, Solidity
smart contracts for blockchain operations, and Ganache for local blockchain deployment. Experimental results
demonstrate that the proposed system improves medicine traceability, enhances verification reliability, and provides
better counterfeit detection compared to traditional QR-based verification systems.
Keywords :
Blockchain, Pharmaceutical Supply Chain, Counterfeit Detection, Drug Traceability, QR Verification, Smart Contracts, Ownership Tracking.
References :
- A. Alkhader, M. Salah, and A. Jayousi, “PharmaChain: A Blockchain to Ensure Counterfeit Free Pharmaceutical Supply Chain,” arXiv preprint arXiv:2202.02592, 2022.
- M. Abdel-Basset, R. Mohamed, and V. Chang, “Protected QR Code-based Anti-counterfeit System for Pharmaceutical Manufacturing,” arXiv preprint arXiv:2404.07831, 2024.
- S. Sharma, P. Gupta, and R. Kumar, “Scalable Blockchain-Based Solution for Drug Tracking in Pharmaceutical Supply Chain,” Computers and Electrical Engineering, vol. 118, 2025.
- Y. Chen, H. Lin, and K. Wang, “A Blockchain-Based Framework for Drug Security: Leveraging EdDSA to Prevent Counterfeiting,” Smart Health Journal, vol. 35, 2025.
- M. Elhoseny and A. Singh, “Blockchain Non-Fungible Token for Effective Drug Traceability System,” Engineering, Technology & Applied Science Research, vol. 15, no. 2, 2025.
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- K. Christidis and M. Devetsikiotis, “Blockchains and Smart Contracts for the Internet of Things,” IEEE Access, vol. 4, pp. 2292–2303, 2016.
- S. Saberi, M. Kouhizadeh, J. Sarkis, and L. Shen, “Blockchain Technology and Its Relationships to Sustainable Supply Chain Management,” International Journal of Production Research, vol. 57, no. 7, pp. 2117–2135, 2019.
- F. Tian, “An Agri-food Supply Chain Traceability System for China Based on RFID & Blockchain Technology,” IEEE International Conference on Service Systems and Service Management, 2016.
Counterfeit medicines have become a major challenge in pharmaceutical supply chains, leading to serious risks
for patient safety and healthcare reliability. Traditional medicine tracking systems mainly rely on centralized databases
and static QR verification methods, which are vulnerable to data manipulation and QR duplication attacks. To address
these issues, this paper proposes a Blockchain-Based Drug Traceability and Intelligent Counterfeit Detection System that
enhances medicine verification using blockchain technology and software-level counterfeit detection mechanisms.
The proposed system integrates blockchain-based medicine registration, QR code verification, ownership transfer
tracking, scan history monitoring, and suspicious activity detection to improve transparency and traceability across the
pharmaceutical supply chain. Medicines are registered and stored securely using smart contracts, while QR codes are
generated for product verification. In addition, the system identifies possible counterfeit activities through duplicate scan
detection, ownership validation, repeated scan monitoring, and already-sold product verification.
The system is implemented using React.js for the frontend, Node.js and Express.js for backend services, Solidity
smart contracts for blockchain operations, and Ganache for local blockchain deployment. Experimental results
demonstrate that the proposed system improves medicine traceability, enhances verification reliability, and provides
better counterfeit detection compared to traditional QR-based verification systems.
Keywords :
Blockchain, Pharmaceutical Supply Chain, Counterfeit Detection, Drug Traceability, QR Verification, Smart Contracts, Ownership Tracking.