Authors :
Suresh Gajendran; Devi sri Rajaraman; Damodara kumaran; Ragasudha Veeramani; Mustaq Ahamed
Volume/Issue :
Volume 8 - 2023, Issue 8 - August
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/mwwdb5wh
DOI :
https://doi.org/10.5281/zenodo.8323396
Abstract :
Background: Locally advanced breast cancer
encompasses a heterogeneous collection of breast
neoplasms, constituting approximately 10 to 20% of
newly diagnosed breast cancer cases annually. The
patient often presents with an ulcerative lesion in the
breast with foul-smelling or bloody discharge associated
with supra clavicular lymphadenopathy and axillary
lymphadenopathy. Case report: In this study, we
reported a case of a 48-year-old female with complaints
of an ulcerated lesion with severe pain over the right
breast and foul-smelling serosanguinous discharge from
the ulcer. Later, it was diagnosed as a case of carcinoma
of the right breast stage cT4bN1Mx. The patient was
given neoadjuvant chemotherapy and three sessions of
hyperthermia per week for 22 sessions. Results: The
tumor responded well to neoadjuvant chemotherapy and
hyperthermia, converting the inoperable tumor into an
operable tumor. Conclusion: Combined neoadjuvant
chemotherapy and hyperthermia significantly reduce the
size of locally advanced breast cancer by converting it
into an operable one, and there was a reduction in pain
over the ulcer, improving the patient's quality of life.
Keywords :
Breast Cancer, Chemosensitizer, Chemotherapy, Hyperthermia, Neoplasm.
Background: Locally advanced breast cancer
encompasses a heterogeneous collection of breast
neoplasms, constituting approximately 10 to 20% of
newly diagnosed breast cancer cases annually. The
patient often presents with an ulcerative lesion in the
breast with foul-smelling or bloody discharge associated
with supra clavicular lymphadenopathy and axillary
lymphadenopathy. Case report: In this study, we
reported a case of a 48-year-old female with complaints
of an ulcerated lesion with severe pain over the right
breast and foul-smelling serosanguinous discharge from
the ulcer. Later, it was diagnosed as a case of carcinoma
of the right breast stage cT4bN1Mx. The patient was
given neoadjuvant chemotherapy and three sessions of
hyperthermia per week for 22 sessions. Results: The
tumor responded well to neoadjuvant chemotherapy and
hyperthermia, converting the inoperable tumor into an
operable tumor. Conclusion: Combined neoadjuvant
chemotherapy and hyperthermia significantly reduce the
size of locally advanced breast cancer by converting it
into an operable one, and there was a reduction in pain
over the ulcer, improving the patient's quality of life.
Keywords :
Breast Cancer, Chemosensitizer, Chemotherapy, Hyperthermia, Neoplasm.
