Authors :
Archana; A. Mounika; D. Suneetha Devi; N. Sumalatha; Fatema Ali Khan; Vasavi Mohan
Volume/Issue :
Volume 8 - 2023, Issue 6 - June
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/3bkc9xt5
DOI :
https://doi.org/10.5281/zenodo.8311190
Abstract :
The Global concern regarding new multidrug
resistant pathogenic microbial strains developing due to
increased usage and misuse of antibiotics has paved the
way for reviving an alternate plant based safe and
effective medicine which targets pathogens without
rendering them drug resistant. Plants which are a
crucial part of our daily diet tend to possess potent
antimicrobial compounds, it is therefore imperative to
screen these plants for their antimicrobial activity, thus
providing an alternate readily available source of
medicine to combat the various pathogenic microbial
infectious agents. The present study was carried out to
evaluate the antimicrobial activity of plant extracts that
we use in day to day lives. The antimicrobial potential of
two different plant extracts were screened against six
pathogenic microorganisms. The methanolic, ethanolic
extracts of Aloe vera and Mentha piperita were subjected
to a test of the antimicrobial properties by agar well
diffusion method. The results indicated that the extracts
of Mentha piperita exhibited potent antimicrobial
properties. The highest antimicrobial activity was
observed in the methanolic extract of Mentha piperita
against Bacillus subtilis followed by ethanolic extract
against Bacillus subtilis. Standard drugs were used for
comparing the inhibitory action of plant extracts against
commercially available antibiotics such as Gentamicin,
Penicillin-G and Chloramphenicol against the bacteria.
The organic solvents such as n-hexane was also used for
testing the antimicrobial activity. The leaf extracts
showed moderate to high activity against both Gram
positive and Gram negative bacteria. When the
antimicrobial properties of both the plants were
compared the extract of Mentha piperita showed higher
antimicrobial properties than Aloe vera. This shows that
the Mentha piperita possesses effective compounds which
are responsible for eliminating the pathogenic bacteria,
and the antimicrobial activity was due to the presence of
various bioactive compounds such as the alkaloids,
flavonoids, steroids and phenolic compounds present in
the organic extracts.
The Global concern regarding new multidrug
resistant pathogenic microbial strains developing due to
increased usage and misuse of antibiotics has paved the
way for reviving an alternate plant based safe and
effective medicine which targets pathogens without
rendering them drug resistant. Plants which are a
crucial part of our daily diet tend to possess potent
antimicrobial compounds, it is therefore imperative to
screen these plants for their antimicrobial activity, thus
providing an alternate readily available source of
medicine to combat the various pathogenic microbial
infectious agents. The present study was carried out to
evaluate the antimicrobial activity of plant extracts that
we use in day to day lives. The antimicrobial potential of
two different plant extracts were screened against six
pathogenic microorganisms. The methanolic, ethanolic
extracts of Aloe vera and Mentha piperita were subjected
to a test of the antimicrobial properties by agar well
diffusion method. The results indicated that the extracts
of Mentha piperita exhibited potent antimicrobial
properties. The highest antimicrobial activity was
observed in the methanolic extract of Mentha piperita
against Bacillus subtilis followed by ethanolic extract
against Bacillus subtilis. Standard drugs were used for
comparing the inhibitory action of plant extracts against
commercially available antibiotics such as Gentamicin,
Penicillin-G and Chloramphenicol against the bacteria.
The organic solvents such as n-hexane was also used for
testing the antimicrobial activity. The leaf extracts
showed moderate to high activity against both Gram
positive and Gram negative bacteria. When the
antimicrobial properties of both the plants were
compared the extract of Mentha piperita showed higher
antimicrobial properties than Aloe vera. This shows that
the Mentha piperita possesses effective compounds which
are responsible for eliminating the pathogenic bacteria,
and the antimicrobial activity was due to the presence of
various bioactive compounds such as the alkaloids,
flavonoids, steroids and phenolic compounds present in
the organic extracts.
