Authors :
Kreena Patel; Naiya Patel; M. A. Gupta; Dr. C.N. Patel
Volume/Issue :
Volume 9 - 2024, Issue 2 - February
Google Scholar :
https://tinyurl.com/yh6abccv
Scribd :
https://tinyurl.com/3nydx6as
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24FEB1356
Abstract :
Stimuli-sensitive systems are a state of
reactivity to sensory stimulation or excitability. These
systems respond to changes in the body’s physiology due
to environmental factors such as temperature, enzymes,
glucose, magnetic fields, redox reactions, ions, and more.
They are particularly useful for the controlled and
sustained delivery of drugs in the body. Controlled drug
delivery has become a standard criterion in modern
pharmaceutical product design, with ongoing intensive
research aimed at achieving a superior drug product
characterized by effectiveness, reliability, and safety.
These stimuli-sensitive systems are employed in various
forms for different purposes, including parenteral,
ocular, peroral, rectal, vaginal, nasal, dermal, and
transdermal drug delivery. This study focuses on the
latest advancements in stimuli-sensitive drug delivery
systems, aiming to address the limitations of traditional
therapeutic methods. The goal is to achieve targeted drug
release in specific areas using various endogenous and
exogenous stimuli. This allows for personalized and
patient-centric treatment strategies. The development of
stimuli-sensitive drug delivery systems remains a
significant human endeavor for successful drug delivery,
given the various shortcomings of existing conventional
systems. To overcome these limitations, various stimuli-
sensitive drug delivery systems (DDSs) have been
developed in recent years.
Keywords :
Endogenous Stimuli, Exogenous Stimuli, Stimuli Sensitive Drug Delivery Systems, Stimuli Responsive Drug Delivery Systems.
Stimuli-sensitive systems are a state of
reactivity to sensory stimulation or excitability. These
systems respond to changes in the body’s physiology due
to environmental factors such as temperature, enzymes,
glucose, magnetic fields, redox reactions, ions, and more.
They are particularly useful for the controlled and
sustained delivery of drugs in the body. Controlled drug
delivery has become a standard criterion in modern
pharmaceutical product design, with ongoing intensive
research aimed at achieving a superior drug product
characterized by effectiveness, reliability, and safety.
These stimuli-sensitive systems are employed in various
forms for different purposes, including parenteral,
ocular, peroral, rectal, vaginal, nasal, dermal, and
transdermal drug delivery. This study focuses on the
latest advancements in stimuli-sensitive drug delivery
systems, aiming to address the limitations of traditional
therapeutic methods. The goal is to achieve targeted drug
release in specific areas using various endogenous and
exogenous stimuli. This allows for personalized and
patient-centric treatment strategies. The development of
stimuli-sensitive drug delivery systems remains a
significant human endeavor for successful drug delivery,
given the various shortcomings of existing conventional
systems. To overcome these limitations, various stimuli-
sensitive drug delivery systems (DDSs) have been
developed in recent years.
Keywords :
Endogenous Stimuli, Exogenous Stimuli, Stimuli Sensitive Drug Delivery Systems, Stimuli Responsive Drug Delivery Systems.
