Lumpy skin disease is a life threatening disease mainly seen in cattle's and buffalo's. It possesses a double stranded DNA genome which encodes 30 duplicates of poxvirus proteins, structural as well as nonstructural. In 1929, the first case of lumpy was noted in Zambia then, it spread to Andaman and Nicobar, northern, western states, 8 states of India, and Union Territory as well. From last 10 years, LSD has expanded rapidly into Eastern Europe and China. Due to this virus, approximately 7300 cows were deceased and more than 1.60 lakhs were affected. LSDV leads to infertility in males and lose of milk production in females. Virus can be directly transmitted by sharing food and water with infected animals or by infected animals nasal and salivary discharge or by sucking of milk by calves as well as Insects that feed on blood (arthropods vectors) transmit the disease indirectly i.e. mosquitoes, butterflies and ticks. South-East Europe controlled this viral infection through use of the live-attenuated LSDV vaccine based upon the Neethling strain of the virus, but this vaccine can also cause adverse reaction, with clinical signs similar to infections with virulent LSDV. Different medicines and home remedies show positive results against infected cattle's. There are various test performed for the analysis of the lumpy virus.

Keywords : Lumpy Skin Disease, Transmission, Hematophagous Vectors, Prevention, Treatments, Herbal Remedies.