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AI-Driven Automated Incident Response in Healthcare Cybersecurity: A Systematic Review of SOAR Frameworks, IoMT Security, and Emerging Trends


Authors : Ghanakshari Khandre; Shripad Bhide

Volume/Issue : Volume 11 - 2026, Issue 5 - May


Google Scholar : https://tinyurl.com/3hzpx7ay

Scribd : https://tinyurl.com/rfamdp84

DOI : https://doi.org/10.38124/ijisrt/26May1548

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Modern healthcare infrastructures face an escalating spectrum of cyber threats, driven in large part by their growing reliance on tightly integrated digital ecosystems — spanning electronic health records, cloud platforms, and networked clinical devices. This exposure is compounded by the rapid proliferation of the Internet of Medical Things (IoMT), a domain characterized by resource-constrained endpoints, inconsistent patch cycles, and legacy communication protocols ill-suited to contemporary security demands. Concurrently, artificial intelligence and machine learning have emerged as promising instruments for advancing cyber threat detection. Yet a persistent and consequential gap remains: the transition from detection to effective, automated response. Though conceptually intertwined, these two functions present markedly different operational realities. Current literature disproportionately favors detection-centric approaches, leaving automated incident response comparatively underexplored. This paper offers a systematic review of AI-driven automated incident response in the context of healthcare cybersecurity. It critically examines the deployment of Security Orchestratioshrin, Automation, and Response (SOAR) frameworks, delineates security challenges endemic to IoMT environments, and surveys emerging intelligent defense paradigms. Following a PRISMA-guided methodology, relevant literature was drawn from IEEE Xplore, SpringerLink, PubMed, Google Scholar, and arXiv, encompassing publications from 2019 to 2026. A rigorous multi-stage screening of 1,499 initial records, governed by predefined inclusion criteria, yielded 20 studies for substantive analysis. The findings reveal a consistent pattern: while AI-based detection models attain strong performance benchmarks, the operationalization of automated response within clinical settings remains nascent. SOAR adoption continues to mature slowly, and prevailing approaches frequently fall short in delivering real-time mitigation and recovery. Compounding these limitations are dependence on narrow benchmark datasets, insufficient model interpretability for clinical contexts, and inadequate incorporation of privacy-preserving methodologies such as federated learning. Taken together, this review makes a compelling case for end-to-end security architectures that transcend detection alone. Next-generation systems must embed SOAR capabilities across the full incident response lifecycle, positioning healthcare organizations to adopt cybersecurity solutions that are not only technically robust but practically deployable at scale.

References :

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Modern healthcare infrastructures face an escalating spectrum of cyber threats, driven in large part by their growing reliance on tightly integrated digital ecosystems — spanning electronic health records, cloud platforms, and networked clinical devices. This exposure is compounded by the rapid proliferation of the Internet of Medical Things (IoMT), a domain characterized by resource-constrained endpoints, inconsistent patch cycles, and legacy communication protocols ill-suited to contemporary security demands. Concurrently, artificial intelligence and machine learning have emerged as promising instruments for advancing cyber threat detection. Yet a persistent and consequential gap remains: the transition from detection to effective, automated response. Though conceptually intertwined, these two functions present markedly different operational realities. Current literature disproportionately favors detection-centric approaches, leaving automated incident response comparatively underexplored. This paper offers a systematic review of AI-driven automated incident response in the context of healthcare cybersecurity. It critically examines the deployment of Security Orchestratioshrin, Automation, and Response (SOAR) frameworks, delineates security challenges endemic to IoMT environments, and surveys emerging intelligent defense paradigms. Following a PRISMA-guided methodology, relevant literature was drawn from IEEE Xplore, SpringerLink, PubMed, Google Scholar, and arXiv, encompassing publications from 2019 to 2026. A rigorous multi-stage screening of 1,499 initial records, governed by predefined inclusion criteria, yielded 20 studies for substantive analysis. The findings reveal a consistent pattern: while AI-based detection models attain strong performance benchmarks, the operationalization of automated response within clinical settings remains nascent. SOAR adoption continues to mature slowly, and prevailing approaches frequently fall short in delivering real-time mitigation and recovery. Compounding these limitations are dependence on narrow benchmark datasets, insufficient model interpretability for clinical contexts, and inadequate incorporation of privacy-preserving methodologies such as federated learning. Taken together, this review makes a compelling case for end-to-end security architectures that transcend detection alone. Next-generation systems must embed SOAR capabilities across the full incident response lifecycle, positioning healthcare organizations to adopt cybersecurity solutions that are not only technically robust but practically deployable at scale.

Paper Submission Last Date
30 - June - 2026

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