Authors :
Nancy; Dr. Neelam Vashist
Volume/Issue :
Volume 8 - 2023, Issue 9 - September
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/2p8rbvts
DOI :
https://doi.org/10.5281/zenodo.8402929
Abstract :
Researchers frequently utilize naturally
occurring coumarins, which exhibit a broad range of
actions like antioxidant effects, anti-inflammatory
capabilities, anticancer potential, MAO-B inhibiting
characteristics, and antimicrobial attributes, as a
foundation for the development of innovative synthetic
and semi-synthetic therapeutic agents based on
coumarin. Oxygen-containing heterocyclic compounds
are prevalent in both natural and synthetic substances.
Coumarins are widely recognized as prominent
heterocycles, characterized by the presence of a single
oxygen atom within their ring structures. These
compounds serve as versatile scaffolds with numerous
applications, such as anti-HIV agents, pain relievers,
antihistamines, insecticides, dyes, herbicides, sensitizers,
fragrances, ingredients in cosmetics, and additives in the
food industry. Because of their wide-ranging uses in both
manufacturing and pharmaceutical industry sectors,
numerous Chemists have exhibited significant interest in
these substances. This review aims to emphasize various
approaches for harnessing the interactions involving the
coumarin moiety, which stands out as one of the most
effective classes of heterocycles. Special emphasis has
been placed on exploring the potential of coumarins as a
vital scaffold in drug development, along with their
usefulness as fluorescent markers for tasks like prodrug
activation, metal sensing, and diagnostics This review
brings together various research findings concerning the
creation of diverse coumarin hybrids and categorizes
them according to their therapeutic applications. Within
this context, we conduct an examination of the current
trends and pertinent subjects pertaining to coumarin
and its derivative compounds.
Keywords :
Coumarin, Heterocycle, Therapeutic uses.
Researchers frequently utilize naturally
occurring coumarins, which exhibit a broad range of
actions like antioxidant effects, anti-inflammatory
capabilities, anticancer potential, MAO-B inhibiting
characteristics, and antimicrobial attributes, as a
foundation for the development of innovative synthetic
and semi-synthetic therapeutic agents based on
coumarin. Oxygen-containing heterocyclic compounds
are prevalent in both natural and synthetic substances.
Coumarins are widely recognized as prominent
heterocycles, characterized by the presence of a single
oxygen atom within their ring structures. These
compounds serve as versatile scaffolds with numerous
applications, such as anti-HIV agents, pain relievers,
antihistamines, insecticides, dyes, herbicides, sensitizers,
fragrances, ingredients in cosmetics, and additives in the
food industry. Because of their wide-ranging uses in both
manufacturing and pharmaceutical industry sectors,
numerous Chemists have exhibited significant interest in
these substances. This review aims to emphasize various
approaches for harnessing the interactions involving the
coumarin moiety, which stands out as one of the most
effective classes of heterocycles. Special emphasis has
been placed on exploring the potential of coumarins as a
vital scaffold in drug development, along with their
usefulness as fluorescent markers for tasks like prodrug
activation, metal sensing, and diagnostics This review
brings together various research findings concerning the
creation of diverse coumarin hybrids and categorizes
them according to their therapeutic applications. Within
this context, we conduct an examination of the current
trends and pertinent subjects pertaining to coumarin
and its derivative compounds.
Keywords :
Coumarin, Heterocycle, Therapeutic uses.
