Authors :
Abhimanyu Dhawalgi; Santhosh Babu; Ashwin Shetty; Vivek S
Volume/Issue :
Volume 8 - 2023, Issue 1 - January
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3I2gsfg
DOI :
https://doi.org/10.5281/zenodo.7614273
Abstract :
A 43 year old male presented with complaints of neck
pain radiating to bilateral upper limb with weakness of
bilateral upper limbs. Examination revealed a loss of
cervical lordosis with restricted range of motion of the
cervical spine .Neurological examination revealed a
weakness of finger abduction and adduction. Blood
investigations showed an elevated erythrocyte
sedimentation rate, while the rest were within normal
limits.MRI scan of the cervical spine showed an
hyperintense lesion of the first thoracic vertebral body. CT
guided biopsy was attempted followed by open biopsy of the
lesion and specimen was sent for histopathological
examination which was later reported as Langerhans cell
histiocytosis and the patient was treated with chemotherapy
for the same.
Despite the rarity of the condition, the possibility of
LCH should be taken into account in these circumstances.
This case shows the role of chemotherapy in management
and draws attention towards early detection in order to
prevent neurological complications with respect to the
rarity of the disease and the site of the bone involvement.
Keywords :
Langerhans Cell Histiocytosis, Chemotherapy.
A 43 year old male presented with complaints of neck
pain radiating to bilateral upper limb with weakness of
bilateral upper limbs. Examination revealed a loss of
cervical lordosis with restricted range of motion of the
cervical spine .Neurological examination revealed a
weakness of finger abduction and adduction. Blood
investigations showed an elevated erythrocyte
sedimentation rate, while the rest were within normal
limits.MRI scan of the cervical spine showed an
hyperintense lesion of the first thoracic vertebral body. CT
guided biopsy was attempted followed by open biopsy of the
lesion and specimen was sent for histopathological
examination which was later reported as Langerhans cell
histiocytosis and the patient was treated with chemotherapy
for the same.
Despite the rarity of the condition, the possibility of
LCH should be taken into account in these circumstances.
This case shows the role of chemotherapy in management
and draws attention towards early detection in order to
prevent neurological complications with respect to the
rarity of the disease and the site of the bone involvement.
Keywords :
Langerhans Cell Histiocytosis, Chemotherapy.
